Now showing items 1027-1046 of 1231

    • Rifampin-warfarin interaction in a mitral valve replacement patient receiving rifampin for infective endocarditis: a case report 

      Fahmi, Amr Mohamed; Abdelsamad, Osama; Elewa, Hazem ( SpringerOpen , 2016 , Article)
      Warfarin therapy is associated with many drug interactions that may cause a significant alteration in its anticoagulant effect. Rifampin is a widely used antimicrobial that has major interactions with several medications ...
    • Risk communication with Arab patients with cancer: a qualitative study of nurses and pharmacists 

      Wilbur, Kerry; Babiker, Alya; Al-Okka, Maha; Jumaat, Ebaa; Al-Yafei, Sumaya M. Al Saadi; ... more authors ( BMJ Publishing Group , 2015 , Article)
      Objectives To explore pharmacist and nurse views and experiences in educating patients regarding their treatment safety and tolerability as well as the roles of other professions in this regard. Design In this qualitative ...
    • Rivaroxaban Pharmacokinetics in Obese Subjects: A Systematic Review 

      Alalawneh, Majdoleen; Awaisu, Ahmed; Rachid, Ousama ( Springer Nature , 2022 , Article)
      Venous thromboembolism (VTE) is a leading cause of morbidity and mortality globally. The direct oral anticoagulants, including rivaroxaban, are relatively novel therapeutic options in the treatment and prevention of VTE. ...
    • The role of amyloids in Alzheimer's and Parkinson's diseases 

      Parveen, Salahuddin; Fatima, Munazza Tamkeen; Uversky, Vladimir N.; Khan, Rizwan Hasan; Islam, Zeyaul; ... more authors ( Elsevier , 2021 , Article)
      With varying clinical symptoms, most neurodegenerative diseases are associated with abnormal loss of neurons. They share the same common pathogenic mechanisms involving misfolding and aggregation, and these visible aggregates ...
    • Role of HMGB1 and its associated signaling pathways in human malignancies 

      Sourour, Idoudi; Bedhiafi, Takwa; Pedersen, Shona; Elahtem, Mohamed; Alremawi, Izzaldin; ... more authors ( Elsevier , 2023 , Article)
      The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ...
    • Role of methylglyoxal in diabetic cardiovascular and kidney diseases: Insights from basic science for application into clinical practice 

      Sankaralingam, Sowndramalingam; Ibrahim, Angham; Rahman, M. D.Mizanur; Eid, Ali H.; Munusamy, Shankar ( Bentham Science Publishers , 2018 , Other)
      Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. ...
    • The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells. 

      Attafi, Ibraheem M; Bakheet, Saleh A; Korashy, Hesham M ( Taylor & Francis , 2019 , Article)
      Lead (Pb) is recognized as the first heavy metal of the top six toxic air pollutants threatening human health and the second hazardous substance. Pb exposure is associated with lung impairment and high incidences of lung ...
    • The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity 

      Suleiman, Muna; Al Najjar, Afnan; Zakaria, Zain Z.; Ahmed, Rashid; Yalcin, Huseyin C.; ... more authors ( Springer , 2023 , Article Review)
      Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ...
    • Role of pharmacist in cardiovascular disease-related health promotion and in hypertension and dyslipidemia management: A cross-sectional study in the State of Qatar 

      El Hajj, Maguy Saffouh; Mahfoud, Ziyad R.; Al Suwaidi, Jassim; Alkhiyami, Dania; Alasmar, Aya Riyad ( Blackwell Publishing Ltd , 2016 , Article)
      Rationale, aims and objectives In Qatar, cardiovascular diseases (CVD) have recently become the leading cause of morbidity and mortality. Prevention, detection and management of CVD risk factors reduce CVD chance. The study ...
    • Role of pharmacists in the application of the transtheoretical model approach to enhance medication adherence in chronic diseases 

      Arafat, Yara; Ibrahim, Mohamed Izham Mohamed; Awaisu, Ahmed ( Society of Hospital Pharmacists of Australia , 2016 , Article)
      Adherence to prescribed medications is one of the most important aspects contributing to successful treatment. Medication adherence through self-management of chronic diseases is thought to be necessary to achieve improvements ...
    • Role of primary care pharmacists in the post-hospital discharge care of patients: a scoping review protocol 

      Yahya, Faiza; Nazar, Hamde; Hadi, Muhammad Abdul ( BMC , 2022 , Article)
      Background: Evidence has shown that there is a significant problem with medication safety when patients are transferred between settings. The role of community pharmacists and hospital pharmacists in facilitating transition ...
    • The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance. 

      Abdelsalam, Shahenda S; Korashy, Hesham M; Zeidan, Asad; Agouni, Abdelali ( MDPI , 2019 , Article Review)
      Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
    • Role of RAS signaling in ovarian cancer 

      Uddin, Shahab; Therachiyil, Lubna; Anand, Anjana; Azmi, Abdullah; Bhat, Ajaz; ... more authors ( Taylor & Francis , 2022 , Article)
      The RAS family of proteins is among the most frequently mutated genes in human malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy, RAS, especially KRAS mutational status at codons 12, 13, and ...
    • Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia 

      Kuttikrishnan S.; Siveen K.S.; Prabhu K.S.; Khan A.Q.; Akhtar S.; ... more authors ( Taylor and Francis Ltd , 2019 , Article)
      Sanguinarine (Sang), a plant-derived compound isolated from the roots of Sanguinaria canadensis was evaluated for its potential pro-apoptotic effects in precursor B acute lymphoblastic leukemia (Pre-ALL) cell lines. Treatment ...
    • SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs 

      Shalaby, Raed; Petzer, Jacobus P.; Petzer, Anél; Ashraf, Usman M.; Atari, Ealla; ... more authors ( Taylor and Francis Ltd. , 2019 , Article)
      The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. ...
    • SARS-CoV-2: An Analysis of the Vaccine Candidates Tested in Combatting and Eliminating the COVID-19 Virus 

      Elmancy, Laila; Alkhatib, Hala; Daou, Anis ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), better known as COVID-19, is a highly contagious virus, transferable via air droplets from close human-human contact. The pandemic has led to over 6.5 million ...
    • Scale development on consumer behavior toward counterfeit drugs in a developing country: A quantitative study exploiting the tools of an evolving paradigm 

      Alfadl, A.A.; Ibrahim, Mohamed Izham Mohamed; Hassali, M.A. Ahmad (2013 , Article)
      Background: Although desperate need and drug counterfeiting are linked in developing countries, little research has been carried out to address this link, and there is a lack of proper tools and methodology. This study ...
    • Scholarly publishing depends on peer reviewers 

      Fernandez-Llimos F.; Berti A.D.; Yeung D.; Yusuff K.B.; El Zowalaty M.E.; ... more authors ( Grupo de Investigacion en Atencion Farmaceutica , 2018 , Article)
      The peer-review crisis is posing a risk to the scholarly peer-reviewed journal system. Journals have to ask many potential peer reviewers to obtain a minimum acceptable number of peers accepting reviewing a manuscript. ...
    • Scope, content and quality of clinical pharmacy practice guidelines: a systematic review 

      Paudyal, Vibhu; Okuyan, Betul; Henman, Martin Charles; Stewart, Derek; Fialová, Daniela; ... more authors ( Springer Nature , 2023 , Article)
      Background: Guidelines for pharmacy practitioners regarding various clinical pharmacy activities have been published in a number of countries. There is a need to review the guidelines and identify the scope of activities ...
    • A Scoping Review of Antimicrobial Stewardship Teaching in Pharmacy Education Curricula. 

      Nasr, Ziad G; Abbara, Duha M; Wilby, Kyle J ( American Association of Colleges of Pharmacy (AACP) , 2021 , Article)
      To conduct a scoping review of the existing literature to identify published studies on innovative teaching and assessment practices for antimicrobial stewardship in the Doctor of Pharmacy curriculum and to provide a ...