Browsing Pharmacy Research by Title
Now showing items 1144-1163 of 1275
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Synthesis And Pharmacological Screening Of Novel Piperine Analogs For Potential In Vitro Protection From Endoplasmic Reticulum Stress
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: The endoplasmic reticulum (ER) is the chief organelle involved in protein homeostasis. Perturbations to the ER protein folding machinery caused by hyperlipidemia, hyperglycemia or hypoglycemia has been shown ... -
Synthesis of curcuma longa doped cellulose grafted hydrogel for catalysis, bactericidial and insilico molecular docking analysis
( Elsevier , 2023 , Article)Curcumin (diferuloylmethane), the primary curcuminoid in turmeric rhizome, has been acknowledged as a bioactive compound for numerous pharmacological activities. Nonetheless, the hydrophobic nature, rapid metabolism, and ... -
Synthesis, characterization & cytocompatibility of poly (diol-co-tricarballylate) based thermally crosslinked elastomers for drug delivery & tissue engineering applications
( Elsevier Ltd , 2018 , Article)The aim of this study was to investigate the synthesis and in vitro characterization of thermoset biodegradable poly (diol-co-tricarballylate) (PDT) elastomeric polymers for the purpose of their use in implantable drug ... -
Synthesizing and Appraising the Quality of the Evidence on Factors Associated with Medication Adherence in Diabetes: A Systematic Review of Systematic Reviews
( Elsevier Inc. , 2017 , Article)Background Nonadherence to medications is a common phenomenon in patients with diabetes. Several studies and systematic reviews have investigated the barriers to medication adherence in diabetes. However, no study has ... -
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
( Elsevier , 2024 , Article)The 3,4-methylenedioxy-alpha-pyrrolidinohexanophenone (MDPHP) is a synthetic cathinone closely related to 3,4-methylenedioxypyrovalerone (MDPV), one of the most common synthetic cathinones present in the “bath salts”. MDPHP ... -
A systematic meta-ethnographic review of the beneficial outcomes of international internships to student pharmacists
( AACP , 2017 , Article)Objective. To describe the benefits that pharmacy students gain by completing international internships as a part of their pharmacy education. Methods. A systematic literature search was conducted from database inception ... -
A Systematic Review of Cost-Effectiveness of Non-Statin Lipid-Lowering Drugs for Primary and Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus
( Elsevier , 2022 , Article)Although studies of nonstatin lipid-lowering therapies have demonstrated cardiovascular benefits; whether these benefits provide good value has not been evaluated in type 2 diabetes mellitus patients. A systematic review ... -
Systematic review of factors affecting pharmaceutical expenditures
( Elsevier Ireland Ltd , 2014 , Article Review)Objective: To systematically identify the main factors contributing to the increase in pharmaceutical expenditures. Methods: A systematic search of published studies was conducted utilising major widely used electronic ... -
A Systematic Review of Instruments for the Assessment of Insomnia in Adults.
( Dove Medical Press , 2020 , Article)Self-reported sleep instruments remain the most practical methods for the assessment of insomnia in clinical practice. This systematic review aims to identify, describe and summarize the psychometric properties of ... -
A systematic review of pharmacist input to metabolic syndrome screening, management and prevention.
( Springer , 2020 , Article Review)Background Metabolic syndrome is a cluster of factors that increase the risk of cardiovascular disease and include: diabetes and prediabetes, abdominal obesity, elevated triglycerides, low high-density lipoprotein cholesterol ... -
A systematic review of the use of simulation and reflection as summative assessment tools to evaluate student outcomes following interprofessional education activities.
( Taylor and Francis , 2022 , Article Review)Despite the increasing emphasis on interprofessional education (IPE) in curricula and the potential benefits for student learning, there appears to be a lack of evidence directing authentic and accurate assessment of ... -
Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents
( Elsevier , 2022 , Article Review)Cancer is one of the leading causes of death and significantly burdens the healthcare system. Due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. The use of natural products as ... -
Targeting dopaminergic system for treating nicotine dependence
( Bentham Science Publishers B.V. , 2016 , Article)Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ... -
Targeting Osteopontin, the Silent Partner of Na+/H+ Exchanger Isoform 1 in Cardiac Remodeling
( Wiley Periodicals, Inc. , 2015 , Article)Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, contributes to cardiac remodeling, which if left unresolved results in heart failure. Understanding the signaling pathways ... -
Taxane anticancer formulations: challenges and achievements
( Academic Press , 2020 , Book chapter)Taxanes represent a prominent anticancer family. Paclitaxel and docetaxel are the most well-known taxanes owing to their activity against many types of cancers. The poor solubility of taxanes in water is a major obstacle ... -
Taxane formulations: From plant to clinic
( Springer International Publishing , 2017 , Book chapter)Taxanes including paclitaxel and docetaxel are highly active against many types of cancers. The main obstacle with developing delivery systems of taxanes is their poor water solubility. In this chapter, taxanes were reviewed ... -
Teaching pharmacovigilance to undergraduate students: Our experience in poor-resource setting
( Wolters Kluwer Health , 2022 , Article)Using medicines associated with adverse drug reactions (ADRs) might cause serious health complications. The pharmacist plays a unique role in monitoring ADRs, either by themselves or with the assistance of other health-care ... -
Telephone versus office-based management of warfarin: Impact on international normalized ratios and outcomes
( Springer-Verlag Tokyo , 2014 , Article)Studies have concluded that telephone-based management of warfarin is an effective alternative to in-office management. High rates of patient and physician satisfaction have been reported with telephone-based monitoring. ... -
Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
( Mary Ann Liebert, Inc. , 2017 , Article)Aims: Circulating microparticles (MPs) from metabolic syndrome patients and those generated from apoptotic T-cells induce endothelial dysfunction; however, the molecular and cellular mechanism(s) underlying in the effects ... -
The Arabic version of the sleep hygiene index: Linguistic validation and cultural adaptation among University students in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Introduction: Sleep is necessary for maintaining adequate health and well-being. However, several behavioral and environmental factors, known as sleep hygiene, could affect sleep quality, contributing to the development ...