Browsing Pharmacy Research by Title
Now showing items 427-446 of 1233
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Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival.
( Frontiers Media , 2020 , Article)Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular abnormalities. Among these EVs, microparticles (MPs) are vesicles directly ... -
Endoplasmic reticulum stress and oxidative stress drive endothelial dysfunction induced by high selenium
( Wiley , 2020 , Article)Selenium is an essential trace element important for human health. A balanced intake is, however, crucial to maximize the health benefits of selenium. At physiological concentrations, selenium mediates antioxidant, ... -
Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes.
( MDPI , 2019 , Article)Physical inactivity and sedentary lifestyle contribute to the widespread epidemic of obesity among both adults and children leading to rising cases of diabetes. Cardiovascular disease complications associated with obesity ... -
Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling
( Elsevier , 2023 , Article)Background: Although some cancer therapies have overt and/or subclinical cardiotoxic effects that increase subsequent cardiovascular risk in breast cancer patients, we have recently shown that the breast tumor itself can ... -
Enhancement in Oral Absorption of Ceftriaxone by Highly Functionalized Magnetic Iron Oxide Nanoparticles.
( MDPI , 2020 , Article)The present study aims at the development, characterization, biocompatibility investigation and oral bioavailability evaluation of ceftriaxone (CFT)-loaded N'-methacryloylisonicotinohydrazide (MIH)-functionalized magnetic ... -
Environmental Factors, Lifestyle Risk Factors, and Host Characteristics Associated With Philadelphia Negative Myeloproliferative Neoplasm: A Systematic Review
( SAGE Publications Ltd , 2021 , Article Review)Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the overproduction of mature myeloid cells and are often associated with an acquired genetic mutation of Janus Kinase2V617F. ... -
Epigenetic inhibitors and their role in cancer therapy
( Elsevier , 2023 , Article)Epigenetic modifications to DNA are crucial for normal cellular and biological functioning. DNA methylation, histone modifications, and chromatin remodeling are the most common epigenetic mechanisms. These changes are ... -
Epigenetic Regulations of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway
( Elsevier , 2020 , Article)Compelling evidence has demonstrated that tumor bulk comprises distinctive subset of cells generally referred as cancer stem cells (CSCs) that has been proposed as a strong sustainer and promoter of tumorigenesis and ... -
Epinephrine in anaphylaxis: Preclinical study of pharmacokinetics after sublingual administration of taste-masked tablets for potential pediatric use
( MDPI AG , 2018 , Article)Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to ... -
Erratum: Increased de novo DNA methylation enzymes in sperm of individuals with varicocele (Cell Journal (2021) 23:4 (389-396) DOI: 10.22074/cellj.2021.7265)
( Royan Institute , 2021 , Other)This article was published in Cell J (Yakhteh), Vol 23, No 4, 2021, on pages 389-396, corresponding author asked us to add another address (5. Biomedical and Pharmaceutical Research Unit, QU Health, Qatar University, Doha, ... -
Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells
( Taylor and Francis Ltd , 2018 , Article)In this study the anticancer activity of paclitaxel-loaded nano-liposomes on glioma cell lines was investigated. Soya phosphatidylcholine:cholesterol (SPC:Chol), hydrogenated soya phosphatidylcholine:cholesterol (HSPC:Chol) ... -
Ethical issues in consenting older adults: academic researchers and community perspectives
( Blackwell Publishing Ltd , 2020 , Article)Objectives: Obtaining informed consents from older adults is surrounded by many ethical and practical challenges. The objective of this study was to evaluate ethical issues and strategies in consenting older adults in ... -
European Society of Clinical Pharmacy: ‘Implementing and scaling sustainable clinical pharmacy’
( Springer Nature , 2024 , Other)All patients and members of the public should have access to high quality clinical pharmacy services, irrespective of country and setting. However, while the literature is awash with a plethora of studies which report small ... -
Eutectics in Pharmacy Curriculum: A Simple Demonstration with Pharmaceutical Relevance
( acs Publications , 2023 , Article)In chemistry, a eutectic mixture refers to a mixture of two or more components at which the lowest possible freezing point is observed. This phenomenon is covered in a wide range of curricula such as physics, chemistry, ... -
Evaluating community pharmacy practice in Qatar using simulated patient method: Acute gastroenteritis management
( Grupo de Investigacion en Atencion Farmaceutica , 2016 , Article)Objective: To evaluate Qatari pharmacists' prescribing, labeling, dispensing and counseling practices in response to acute community-acquired gastroenteritis. Methods: The simulated patient method was used in this study. ... -
Evaluating knowledge, skills, and practice change after an accredited evidence-based medicine course for community pharmacy preceptors
( Elsevier Inc. , 2019 , Article)Introduction: Incorporating evidence-based medicine skills into practice is vital for pharmacists to promote rational medication use while making optimal patient care decisions. The objective of this study was to evaluate ... -
Evaluating prescribing competencies covered in a Canadian-accredited undergraduate pharmacy program in Qatar: A curriculum mapping process
( BioMed Central Ltd , 2020 , Article)Background: The objective of this study was to evaluate the existing Bachelor of Science in Pharmacy [BSc (Pharm)] curriculum at Qatar University College of Pharmacy (QU CPH), for addressing international prescribing ... -
Evaluating the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression
( Pharmainfo Publications , 2018 , Article)Purpose: This study was aimed to evaluate the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression. Methods: One thousand and fourteen ... -
Evaluating the effects of sodium glucose co-transporter -2 inhibitors from a renin–angiotensin–aldosterone system perspective in patients infected with COVID-19: contextualizing findings from the dapagliflozin in respiratory failure in patients with COVID-19 study
( Springer , 2022 , Article Review)Numerous studies demonstrate parallels between CVD, type 2 diabetes mellitus (T2DM) and COVID-19 pathology, which accentuate pre-existing complications in patients infected with COVID-19 and potentially exacerbate the infection ... -
Evaluating the online platform of a blended-learning pharmacist continuing education degree program
( Co-Action Publishing , 2016 , Article)Background: Distance-based continuing education opportunities are increasingly embraced by health professionals worldwide. Methods: To evaluate the online component of a blended-learning degree program for pharmacists, ...