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Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B

Sadaf, Riaz; Abdulrahman, Nabeel; Uddin, Shahab; Jabeen, Ayesha; Gadeau, Alain P.; Fliegel, Larry; Mraiche, Fatima... more authors ... less authors ( Elsevier , 2020 , Article)
Previous studies have established the role of Na+/H+ exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions ...
Effect of SAMe-TT2R2 score and genetic polymorphism on the quality of anticoagulation control in Qatari patients treated with warfarin.

Elewa, Hazem; Qurishi, Iqrah; Abouelhassan, Rawan; Abou Safrah, Salam; Alhamoud, Eman; Bader, Loulia... more authors ... less authors ( Springer Nature , 2020 , Article)
There is no strong evidence on pharmacogenetics role on the quality of INR control after the initiation phase and on the maintenance of stable INR on the long term as measured by the time in therapeutic range (TTR). The ...