تصفح Pharmacy Research حسب الموضوع "S6 kinase"
السجلات المعروضة 1 -- 2 من 2
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Na+/H+ exchanger isoform 1 induced cardiomyocyte hypertrophy involves activation of p90 ribosomal S6 Kinase
( Public Library of Science , 2015 , Article)Studies using pharmacological and genetic approaches have shown that increased activity/expression of the Na+/H+ exchanger isoform 1 (NHE1) play a critical role in the pathogenesis of cardiac hypertrophy. Despite the ... -
Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy
( Public Library of Science , 2015 , Article)Enhanced expression and activity of the Na+/H+ exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin ...