Browsing Pharmacy Research by Subject "bioavailability"
Now showing items 1-4 of 4
-
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
( Elsevier B.V. , 2016 , Article)This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ... -
Instrumentation of Flow-Through USP IV Dissolution Apparatus to Assess Poorly Soluble Basic Drug Products: a Technical Note
( Springer New York LLC , 2016 , Article)Supersaturation and precipitation are common limitations encountered especially with poorly soluble basic drugs. The aims of this work were to explore the pattern of dissolution and precipitation of poorly soluble basic ... -
Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its ... -
Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin
( Taylor and Francis Ltd , 2016 , Article)Context: Vesicular systems have attracted great attention in drug delivery because of their amphiphilicity, biodegradability, non-toxicity and potential for increasing drug bioavailability. Objective: A novel sugar-based ...