Browsing Pharmacy Research by Subject "mTOR"

Now showing items 1-2 of 2

    • Microparticles as Potential Mediators of High Glucose-Induced Renal Cell Injury. 

      Ravindran, Sreenithya; Pasha, Mazhar; Agouni, Abdelali; Munusamy, Shankar ( MDPI , 2019 , Article)
      Diabetic nephropathy (DN) is the most common cause of chronic kidney disease worldwide. Activation of signaling pathways such as the mammalian target of rapamycin (mTOR), extracellular signal-regulated kinases (ERK), ...

    • Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases 

      Pasha, Mazhar; Eid, Ali H.; Eid, Assaad A.; Gorin, Yves; Munusamy, Shankar ( Hindawi , 2017 , Article)
      Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, ...