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Na+/H+ exchanger isoform 1 induced cardiomyocyte hypertrophy involves activation of p90 ribosomal S6 Kinase
(
Public Library of Science
, 2015 , Article)
Studies using pharmacological and genetic approaches have shown that increased activity/expression of the Na+/H+ exchanger isoform 1 (NHE1) play a critical role in the pathogenesis of cardiac hypertrophy. Despite the ...
Obstructive sleep apnea: Management considerations in psychiatric patients
(
Dove Press
, 2015 , Article)
Psychiatric disorders and obstructive sleep apnea (OSA) are often comorbid. However, there is limited information on the impact of psychotropic medications on OSA symptoms, on how to manage psychiatric pharmacotherapy in ...
Medication management during electroconvulsant therapy
(
Dove Press
, 2016 , Article)
Electroconvulsive therapy (ECT) has demonstrated to be highly effective and safe, even life saving for many psychiatric disorders such as major depression, bipolar disorder and schizophrenia. Most patients who require ECT ...
Evaluating community pharmacy practice in Qatar using simulated patient method: Acute gastroenteritis management
(
Grupo de Investigacion en Atencion Farmaceutica
, 2016 , Article)
Objective: To evaluate Qatari pharmacists' prescribing, labeling, dispensing and counseling practices in response to acute community-acquired gastroenteritis. Methods: The simulated patient method was used in this study. ...
The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells.
(
Taylor & Francis
, 2019 , Article)
Lead (Pb) is recognized as the first heavy metal of the top six toxic air pollutants threatening human health and the second hazardous substance. Pb exposure is associated with lung impairment and high incidences of lung ...
Communicating medication risk to cardiovascular patients in Qatar
(
Emerald Group Publishing Ltd.
, 2018 , Article)
Purpose: Patient safety is gaining prominence in health professional curricula. Patient safety must be complemented by teaching and skill development in practice settings. The purpose of this paper is to explore how ...
Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population
(
Nature Publishing Group
, 2019 , Article)
The effectiveness of dapagliflozin in the management of type-2 diabetes mellitus (T2-DM) is an essential issue for establishing a basis for prescribing dapagliflozin. This study aimed to assess the effectiveness of ...
There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East and Southeast Asia.
(
Frontiers Media
, 2019 , Article)
Stroke attacks were found to be present at a younger age in patients from Southeast Asia (SE) and the Middle East (ME) resident in the state of Qatar. Extracellular vesicles (EVs), which are small membrane vesicles with ...
Cost-effectiveness Evaluations Among the Direct Oral Anticoagulants for the Prevention and Treatment of Venous Thromboembolism: Systematic Review
(
SAGE Publications Inc.
, 2019 , Article)
Venous thromboembolism (VTE) is associated with high recurrence, mortality, and cost burden. Direct oral anticoagulants (DOACs) are currently used for VTE treatment, and they offer more benefits over warfarin, despite being ...
Attitudes and practices of community pharmacists and barriers to their participation in public health activities in Yemen: Mind the gap
(
BioMed Central Ltd.
, 2019 , Article)
Background: Patients in Yemen commonly visit community pharmacies to obtain consultation or treatment for common ailments. Community pharmacists have an opportunity to optimize medication use and improve patient outcomes. ...