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Now showing items 351-360 of 403
Medication use problems and factors affecting older adults in primary healthcare
(
Elsevier
, 2023 , Article)
Background: As the largest demographic group utilizing primary healthcare facilities, older adults often face the challenge of managing multiple chronic illnesses, leading to numerous medications. Objective: The present ...
Exploring determinants of antimicrobial prescribing behaviour using the Theoretical Domains Framework
(
Elsevier
, 2024 , Article)
BackgroundFew theoretically-based, qualitative studies have explored determinants of antimicrobial prescribing behaviour in hospitals. Understanding these can promote successful development and implementation of behaviour ...
Impact of pharmaceutical care interventions in improving clinical outcomes among patients with pulmonary tuberculosis: a systematic review
(
Taylor & Francis
, 2024 , Article)
Background: Pharmacists can play an important role in the fight against tuberculosis (TB) through optimising medication use and safety, promoting adherence to anti-TB drugs, and providing patient education. Limited evidence ...
Apabetalone (RVX-208): A Potential Epigenetic Therapy for the Treatment of Cardiovascular, Renal, Neurological, Viral, and Cancer Disorders
(
American Chemical Society (ACS)
, 2024 , Article)
Bromodomain and extra-terminal domain proteins (BET proteins) are epigenetic reader proteins that have been implicated in regulating gene expression through binding to chromatin and interaction with transcription factors. ...
Shrinking the battlefield in cancer therapy: Nanotechnology against cancer stem cells
(
Elsevier
, 2023 , Article)
Cancer remains one of the leading causes of mortality worldwide, presenting a significant healthcare challenge owing to the limited efficacy of current treatments. The application of nanotechnology in cancer treatment ...
Optimizing polypharmacy management in the elderly: a comprehensive European benchmarking survey and the development of an innovative online benchmarking application
(
Frontiers Media
, 2023 , Article)
Background: Polypharmacy, defined as the simultaneous use of multiple medications by a patient, is a worldwide problem of rising prevalence. Paving the way for drug interactions, adverse drug reactions and non-adherence, ...
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ...
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
(
Frontiers Media SA
, 2024 , Article)
In the current study, Neosetophomone B (NSP-B) was investigated for its anti-cancerous potential using network pharmacology, quantum polarized ligand docking, molecular simulation, and binding free energy calculation. Using ...
Perceptions of Yemeni physicians about sources of drug information and factors predicting their choices
(
Open Science Publishers LLP
, 2021 , Article)
High-quality information is a necessary prerequisite for an optimum prescribing decision that enhances patient healthcare outcomes. Therefore, the purpose of this study was to identify the main sources of information used ...
Evaluation of the impact of COVID-19 pandemic on hospital-acquired infections in a tertiary hospital in Malaysia
(
BioMed Central Ltd
, 2023 , Article)
Background: Infection prevention measures are the gold standard for preventing the spread of hospital-acquired infections (HAIs). COVID-19 pandemic caused major disruptions in infection prevention measures, and this has ...