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PLGA-Gold Nanocomposite: Preparation and Biomedical Applications
(
MDPI
, 2022 , Article)
A composite system consisting of both organic and inorganic nanoparticles is an approach
to prepare a new material exhibiting “the best of both worlds”. In this review, we highlight the
recent advances in the preparation ...
Prospects of Curcumin Nanoformulations in Cancer Management
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
There is increasing interest in the use of natural compounds with beneficial pharmacological effects for managing diseases. Curcumin (CUR) is a phytochemical that is reportedly effective against some cancers through its ...
Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes
(
Taylor & Francis
, 2022 , Article)
Arthrospira platensis (A. platensis) aqueous extract has massive amounts of natural products that can be used as future drugs, such as C-phycocyanin, allophycocyanin, etc. This extract was chosen because of its high ...
Characterization and ex vivo evaluation of curcumin nanoethosomes for melanoma treatment
(
Taylor & Francis
, 2022 , Article)
This study aimed at developing curcumin nanoethosomes (Cur-Ets) with superior skin permeation intended for melanoma treatment. Although curcumin is active against many types of skin cancers, a suitable topical formulation ...
A Validated Reverse-Phase High Performance Liquid Chromatography (RP-HPLC) Method for the Quantification of Gamma-Tocotrienol in Tocotrienol Rich Fractions of Crude Palm Oil
(
Bentham
, 2021 , Article)
Background: Palm oil and its constituents have wide applications in food, cosmet-ics and pharmaceutical industries. The tocotrienol-rich fractions of crude palm oil have drawn greater research interest in recent years due ...
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
(
Elsevier
, 2023 , Article)
Colon cancer (CRC) is the second leading cause of death and the third most diagnosed cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity, it is characterized by its poor solubility, low ...
A novel approach of encapsulating curcumin and succinylated derivative in mannosylated-chitosan nanoparticles
(
Elsevier
, 2022 , Article)
Curcumin (CUR) manifests anti-colon cancer activity but suffers from low solubility, bioavailability, and instability, rendering it not as effective as its chemotherapeutic cousins. Here, we conjugate CUR to succinic ...
Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its ...
Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve ...
Solid Dispersion Formulations by FDM 3D Printing—A Review
(
MDPI
, 2022 , Article)
Additive manufacturing (AM) is revolutionizing the way medicines are designed, manufactured, and utilized. Perhaps, AM appears to be ideal for the fit-for-purpose manufacturing of medicines in contrast to the several ...