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The effect of migration on the incidence of new-onset metabolic syndrome in migrants to Qatar
(
Hamad bin Khalifa University Press (HBKU Press)
, 2022 , Article)
Background: There is substantial evidence that migration to Western countries is associated with an increased risk of metabolic syndrome (MetS) 1 . However, there is a paucity of data on the incidence of MetS in migrants ...
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
(
Elsevier
, 2022 , Article)
Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by ...
Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Multiple myeloma (MM) is a hematological disorder characterized by the abnormal expansion of plasma cells in the bone marrow. Despite great advances over the past three decades in discovering the efficacious therapies for ...
Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis
(
Frontiers Media S.A.
, 2022 , Article)
Abnormal expression of Forkhead box protein M1 (FOXM1) and serine/threonine kinase Budding uninhibited by benzimidazoles 1 (BUB1B) contributes to the development and progression of several cancers, including chronic ...