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A survey on the awareness and attitude of pharmacists and doctors towards the application of pharmacogenomics and its challenges in Qatar
(
John Wiley & Sons, Ltd.
, 2015 , Article)
RATIONALE, AIMS AND OBJECTIVES:
Pharmacists are expected to play an important role in applying pharmacogenomics discoveries to patient care. Despite the increased attention to genetic research in Qatar, clinicians' attitudes ...
Economic Evaluations of CYP2C19 Genotype-Guided Antiplatelet Therapy Compared to the Universal Use of Antiplatelets in Patients With Acute Coronary Syndrome: A Systematic Review.
(
SAGE Publications
, 2020 , Article)
Clopidogrel is widely used after the percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) and requires activation by cytochrome P450 (CYP), primarily CYP2C19. Patients with CYP2C19 ...
Telephone versus office-based management of warfarin: Impact on international normalized ratios and outcomes
(
Springer-Verlag Tokyo
, 2014 , Article)
Studies have concluded that telephone-based management of warfarin is an effective alternative to in-office management. High rates of patient and physician satisfaction have been reported with telephone-based monitoring. ...
Strategies to Optimize Dual Antiplatelet Therapy after Coronary Artery Stenting in Acute Coronary Syndrome
(
SAGE Publications Ltd
, 2017 , Article)
The use of aspirin and a P2Y12 receptor antagonist as dual antiplatelet therapy (DAPT) has become the treatment of choice in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention to prevent ...
Exploring the Influence of Language on Assessment Given a Mismatch Between Language of Instruction and Language of Practice
(
Lippincott, Williams & Wilkins
, 2019 , Article)
A phenomenon is occurring in international settings where the language of program delivery and assessment does not match the primary language of practice. It is unknown whether determining competence in English disadvantages ...
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
Cancer-Associated Venous Thromboembolism
(
Springer Healthcare
, 2016 , Article Review)
Cancer patients are at high risk for venous thromboembolism (VTE) which is considered the second leading cause of death among this population. Both cancer and cancer treatment increase this risk. Since the risk of VTE is ...
A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
(
Springer-Verlag France
, 2017 , Article Review)
Genetic variability in drug-metabolizing enzymes and drug transporters is known to influence the pharmacokinetics of many drugs. Antimalarial drugs are a class of agents known to utilize metabolic and elimination pathways ...
Treatment outcomes of fixed-dose combination versus separate tablet regimens in pulmonary tuberculosis patients with or without diabetes in Qatar
(
BioMed Central Ltd.
, 2017 , Article)
Background
Tuberculosis is considered the second most common cause of death due to infectious agent. The currently preferred regimen for treatment of pulmonary tuberculosis (PTB) is isoniazid, rifampin, pyrazinamide, and ...
The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review
(
SAGE Publications Inc.
, 2019 , Article Review)
Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle ...