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Effect of CYP2C19 genetic variants on bleeding and major adverse cardiovascular events in a cohort of Arab patients undergoing percutaneous coronary intervention and stent implantation
(
Lippincott Williams and Wilkins
, 2022 , Article)
Introduction One-third of patients have clopidogrel resistance that may lead to major adverse cardiac events (MACEs). By contrast, it was found that some clopidogrel-treated patients have hyperresponsive platelets that are ...
Nanotechnology in medicine – our experiences
(
Macedonian Pharmaceutical Association
, 2022 , Article)
The success of design criteria for long-circulating drug delivery systems to support membrane receptor-ligand interaction and internalization has been limited and there is a need to develop smarter approaches for efficient ...
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
(
Springer
, 2022 , Article)
Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ...
Identifying the core concepts of pharmacology education: A global initiative
(
Wiley-Blackwell
, 2022 , Article)
Background and Purpose: In recent decades, a focus on the most critical and fundamental concepts has proven highly advantageous to students and educators in many science disciplines. Pharmacology, unlike microbiology, ...
Editorial: Recent advancements in neoadjuvant chemotherapy for specific breast cancer subtypes
(
Frontiers Media S.A.
, 2022 , Article)
Most locally advanced breast cancer patients undergo pre-surgery treatment known as neoadjuvant chemotherapy (NAC). The purpose of NAC is to reduce the tumor’s size and improve surgical outcomes, cosmetic results, and ...