Mechanical & Industrial Engineering: Recent submissions
Now showing items 681-700 of 1396
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Ferritin Nanocage Conjugated Hybrid Hydrogel for Tissue Engineering and Drug Delivery Applications
( American Chemical Society , 2020 , Article)Hydrogels have recently been attractive in various drug delivery and tissue engineering applications because of their structural similarities to the natural extracellular matrix. Despite enormous advances in the application ... -
Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase
( Taylor and Francis Ltd. , 2020 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative representative of a severe respiratory illness resulted in widespread human infections and deaths in nearly all of the countries since late 2019. ... -
Experimental study on the mechanical properties of biological hydrogels of different concentrations
( IOS Press BV , 2020 , Article)BACKGROUND: Biological hydrogels provide a conducive three-dimensional extracellular matrix environment for encapsulating and cultivating living cells. Microenvironmental modulus of hydrogels dictates several characteristics ... -
Cellular response to nanobiomaterials
( Elsevier , 2020 , Book chapter)The application of nanobiomaterials in biomedical field is rapidly processing, especially in the areas where conventional approaches have limited success. Cell fate is mainly influenced by interactions between cells and ... -
Multimodal applications of phytonanoparticles
( Elsevier , 2020 , Book chapter)The emergence of nanotechnology has revolutionized modern life due to its diverse applications in healthcare, agriculture, the environment, and other technological applications. Growing concerns over the toxicity of ... -
Cerium Oxide Nanoparticle Incorporated Electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Membranes for Diabetic Wound Healing Applications
( American Chemical Society , 2020 , Article)Insufficient cell proliferation, cell migration, and angiogenesis are among the major causes for nonhealing of chronic diabetic wounds. Incorporation of cerium oxide nanoparticles (nCeO2) in wound dressings can be a promising ... -
Exploring the interaction of cobalt oxide nanoparticles with Albumin, leukemia cancer cells and pathogenic bacterial by multispectroscopic, docking, cellular and antibacterial approaches
( Dove Medical Press Ltd. , 2020 , Article)Aim: The interaction of NPs with biological systems may reveal useful details about their pharmacodynamic, anticancer and antibacterial effects. Methods: Herein, the interaction of as-synthesized Co3O4 NPs with HSA was ... -
Antimetastatic Activity of Lactoferrin-Coated Mesoporous Maghemite Nanoparticles in Breast Cancer Enabled by Combination Therapy
( American Chemical Society , 2020 , Article)Despite successes in breast cancer treatment, the incidence of metastasis, drug resistance, and toxicity limit the efficacy of current therapeutic modalities. Herein, by designing lactoferrin-doxorubicin-mesoporous maghemite ... -
Plasmonic and chiroplasmonic nanobiosensors based on gold nanoparticles
( Elsevier B.V. , 2020 , Article)Development of optical nanobiosensors has emerged as one of the most important bioresearch areas of interest over the past decades especially in the modern innovations in the design and utilization of sensing platforms. ... -
Rheological characterization of biological hydrogels in aqueous state
( Baqiyatallah University of Medical Sciences , 2020 , Article)Introduction: Biological hydrogels provide a conducive extracellular environment for encapsulating and growing cells and play an important role in regulating cell behavior. Mechanical and rheological properties of hydrogels ... -
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
( Elsevier B.V. , 2020 , Article)Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical ... -
Strategies of enzyme immobilization on nanomatrix supports and their intracellular delivery
( Taylor and Francis Ltd. , 2020 , Article)Enzymes are one of the foundations and regulators for all major biological activities in living bodies. Hence, enormous efforts have been made for enhancing the efficiency of enzymes under different conditions. The use of ... -
Measurements of Elastic Properties of Biological Hydrogels using Atomic Force Microscopy
( Institute of Physics Publishing , 2020 , Conference Paper)Biological hydrogels are widely used as extracellular environment for encapsulating and growing cells. Mechanical properties of hydrogels can influence cell function, mechanotransduction and cellular behavior such as growth, ... -
Gold nanozyme: Biosensing and therapeutic activities
( Elsevier Ltd , 2020 , Article)The utilization of AuNPs in therapeutic applications has been accelerated by discovering their catalytic activity consistent with the activity of natural enzymes. However, to reduce unwanted activities, it is imperative ... -
Emerging applications of biocompatible phytosynthesized metal/metal oxide nanoparticles in healthcare
( Elsevier B.V. , 2020 , Article)Various applications of nanotechnology in healthcare, agriculture, environmental and other technological fields have considerably transformed human life. However, harmful effects of nanomaterials synthesized by traditional ... -
Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
( Elsevier B.V. , 2020 , Article)Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ... -
The effects of nickel oxide nanoparticles on structural changes, heme degradation, aggregation of hemoglobin and expression of apoptotic genes in lymphocytes
( Taylor and Francis Ltd. , 2020 , Article)Nickel oxide nanoparticles (NiO NPs) have received great interests in medical and biotechnological applications. However, their adverse impacts against biological systems have not been well-explored. Herein, the influence ... -
Phytochemical-assisted biosynthesis of silver nanoparticles from Ajuga bracteosa for biomedical applications
( Institute of Physics Publishing , 2020 , Article)Silver nanoparticles (AgNPs) synthesized from plant extracts are widely used for the cure of many diseases from fever to cancers. Keeping in view the medicinal value of AgNPs, here we report a cost-effective phytochemical ... -
Secondary metabolites from acridocarpus orientalis inhibits 4T1 cells and promotes mesenchymal stem cells (MSCs) proliferation
( Springer , 2020 , Article)Abstract: Among medicinal plants, Acridocarpus orientalis (AO) possesses a remarkable anti-cancer potential, possibly because of its anti-oxidant property. In this study, the leaf and stem extracts from AO were assessed ... -
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
( Elsevier B.V. , 2020 , Article)Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...