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AuthorJ. Abu-Raddad, Laith
AuthorDargham, Soha
AuthorChemaitelly, Hiam
AuthorCoyle, Peter
AuthorAl Kanaani, Zaina
AuthorAl Kuwari, Einas
AuthorA. Butt, Adeel
AuthorJeremijenko, Andrew
AuthorHassan Kaleeckal, Anvar
AuthorNizar Latif, Ali
AuthorMohammad Shaik, Riyazuddin
AuthorF. Abdul Rahim, Hanan
AuthorK. Nasrallah, Gheyath
AuthorM. Yassine, Hadi
AuthorG. Al Kuwari, Mohamed
AuthorEid Al Romaihi, Hamad
AuthorH. Al-Thani, Mohamed
AuthorAl Khal, Abdullatif
AuthorBertollini, Roberto
Available date2022-08-31T20:27:50Z
Publication Date2022
Publication NamePLoS ONE
Identifierhttp://dx.doi.org/10.1371/journal.pone.0271324
CitationAbu-Raddad, L. J., Dargham, S., Chemaitelly, H., Coyle, P., Al Kanaani, Z., Al Kuwari, E., ... & Bertollini, R. (2022). COVID-19 risk score as a public health tool to guide targeted testing: A demonstration study in Qatar. PloS one, 17(7), e0271324.‏
URIhttp://hdl.handle.net/10576/33608
AbstractWe developed a Coronavirus Disease 2019 (COVID-19) risk score to guide targeted RTPCR testing in Qatar. The Qatar national COVID-19 testing database, encompassing a total of 2,688,232 RT-PCR tests conducted between February 5, 2020-January 27, 2021, was analyzed. Logistic regression analyses were implemented to derive the COVID-19 risk score, as a tool to identify those at highest risk of having the infection. Score cut-off was determined using the ROC curve based on maximum sum of sensitivity and specificity. The score's performance diagnostics were assessed. Logistic regression analysis identified age, sex, and nationality as significant predictors of infection and were included in the risk score. The ROC curve was generated and the area under the curve was estimated at 0.63 (95% CI: 0.63-0.63). The score had a sensitivity of 59.4% (95% CI: 59.1%-59.7%), specificity of 61.1% (95% CI: 61.1%-61.2%), a positive predictive value of 10.9% (95% CI: 10.8%- 10.9%), and a negative predictive value of 94.9% (94.9%-95.0%). The concept and utility of a COVID-19 risk score were demonstrated in Qatar. Such a public health tool can have considerable utility in optimizing testing and suppressing infection transmission, while maximizing efficiency and use of available resources. 2022 Abu-Raddad et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Languageen
PublisherPublic Library of Science
SubjectCOVID-19
Subjectstudy in Qatar
TitleCOVID-19 risk score as a public health tool to guide targeted testing: A demonstration study in Qatar
TypeArticle
Volume Number17


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