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المؤلفHoteit, R.
المؤلفHoteit, Reem
المؤلفYassine, Hadi M.
تاريخ الإتاحة2022-09-12T16:31:56Z
تاريخ النشر2022-06-01
اسم المنشورVaccines
المعرّفhttp://dx.doi.org/10.3390/vaccines10060919
الاقتباسHoteit, R., & Yassine, H. M. (2022). Biological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences. Vaccines, 10(6), 919.‏
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85132704289&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/33887
الملخصSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that belongs to the coronavirus family and is the cause of coronavirus disease 2019 (COVID-19). As of May 2022, it had caused more than 500 million infections and more than 6 million deaths worldwide. Several vaccines have been produced and tested over the last two years. The SARS-CoV-2 virus, on the other hand, has mutated over time, resulting in genetic variation in the population of circulating variants during the COVID-19 pandemic. It has also shown immune-evading characteristics, suggesting that vaccinations against these variants could be potentially ineffective. The purpose of this review article is to investigate the key variants of concern (VOCs) and mutations of the virus driving the current pandemic, as well as to explore the transmission rates of SARS-CoV-2 VOCs in relation to epidemiological factors and to compare the virus’s transmission rate to that of prior coronaviruses. We examined and provided key information on SARS-CoV-2 VOCs in this study, including their transmissibility, infectivity rate, disease severity, affinity for angiotensin-converting enzyme 2 (ACE2) receptors, viral load, reproduction number, vaccination effectiveness, and vaccine breakthrough.
اللغةen
الناشرMDPI
الموضوعclinical consequences
coronavirus disease 2019 (COVID-19)
epidemiological factors
mutations
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs)
العنوانBiological Properties of SARS-CoV-2 Variants: Epidemiological Impact and Clinical Consequences
النوعArticle Review
رقم العدد6
رقم المجلد10
dc.accessType Open Access


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