Browsing Biological & Environmental Sciences by Author "Bradner, James E."
Now showing items 1-2 of 2
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Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation
Alinari, Lapo; Mahasenan, Kiran V.; Yan, Fengting; Karkhanis, Vrajesh; Chung, Ji-Hyun; Smith, Emily M.; Quinion, Carl; Smith, Porsha L.; Kim, Lisa; Patton, John T.; Lapalombella, Rosa; Yu, Bo; Wu, Yun; Roy, Satavisha; De Leo, Alessandra; Pileri, Stefano; Agostinelli, Claudio; Ayers, Leona; Bradner, James E.; Chen-Kiang, Selina; Elemento, Olivier; Motiwala, Tasneem; Majumder, Sarmila; Byrd, John C.; Jacob, Samson; Sif, Said; Li, Chenglong; Baiocchi, Robert A.... more authors ... less authors ( American Society of Hematology , 2015 , Article)Epigenetic events that are essential drivers of lymphocyte transformation remain incompletely characterized. We used models of Epstein-Barr virus (EBV)–induced B-cell transformation to document the relevance of protein ... -
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6
Hu, Yu-Jie; Belaghzal, Houda; Hsiao, Wen-Yu; Qi, Jun; Bradner, James E.; Guertin, David A.; Sif, Said; Imbalzano, Anthony N.... more authors ... less authors ( Oxford University Press , 2015 , Article)Jumonji domain-containing protein 6 (JMJD6) is a nuclear protein involved in histone modification, transcription and RNA processing. Although JMJD6 is crucial for tissue development, the link between its molecular functions ...