Browsing Biological & Environmental Sciences by Subject "NLRP3"

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    • Can Polymorphisms in NLRP3 Inflammasome Complex Be Associated with Postmenopausal Osteoporosis Severity? 

      Guaraná, Werbson Lima; Lima, Camilla Albertina Dantas; Barbosa, Alexandre Domingues; Crovella, Sergio; Sandrin-Garcia, Paula ( MDPI , 2022 , Article)
      The immune system plays a critical role in bone homeostasis and, consequently, in the pathophysiology of postmenopausal osteoporosis (OP) since estrogen deficiency induces the inflammasome and increases production of ...

    • Do inflammasome impact COVID-19 severity? 

      Calado, Maria Beatriz; da Silva Santana, Crislayne Emilly; Crovella, Sergio ( Springer , 2021 , Article Review)
      COVID-19 pandemic has proven to be a dramatic challenge, introducing huge clinical differences that demand extensive investigations. Severe and critical patients may present coagulopathies and microthrombi, which results ...