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Salinomycin induces apoptosis and senescence in breast cancer: Upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation
(
Elsevier
, 2013 , Article)
Background
In the present study, we investigated the effect of Salinomycin on the survival of three human breast cancer cell lines MCF-7, T47D and MDA-MB-231 grown in adherent culture conditions.
Methods
Cell viability ...
Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2
(
American Physiological Society
, 2013 , Article)
The second messenger cyclic AMP (cAMP) plays a vital role in vascular physiology, including vasodilation of large blood vessels. We recently demonstrated cAMP activation of Epac-Rap1A and RhoA-Rho-associated kinase ...
Phytoplankton along the coastal shelf of an oligotrophic hypersaline environment in a semi-enclosed marginal sea: Qatar (Arabian Gulf)
(
Elsevier
, 2013 , Article)
Phytoplankton biomass (chlorophyll a concentration), primary production, abundance, species diversity and species groupings were measured in the coastal waters surrounding Qatar (Arabian Gulf) at 13 stations in February ...
Potential of Photorhabdus temperata K122 bioinsecticide in protecting wheat flour against Ephestia kuehniella
(
Elsevier Ltd
, 2013 , Article)
The present study reports investigations on the insecticidal activity of the entomopathogenic bacterium Photorhabdus temperata K122 against the Mediterranean flour moth Ephestia kuehniella. Cultured in the optimized medium, ...