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Knockout mice: Is it just genetics? Effect of enriched housing on fibulin-4+/- mice
(
Public Library of Science
, 2007 , Article)
Background. Fibulin-4 is an extracellular matrix protein expressed by vascular smooth muscle cells that is essential for maintaining arterial integrity. Fibulin-4-/- mice die just before birth due to arterial hemorrhage, ...
Internalization of metal-organic framework nanoparticles in human vascular cells: Implications for cardiovascular disease therapy
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Alteration of endothelial cells and the underlying vasculature plays a central role in the pathogenesis of various CVDs. The ...