تصفح Research Units حسب المؤلف "Al-Jighefee, Hadeel"
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Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population
Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; Chemaitelly, Hiam; Al Kanaani, Zaina; Al Khal, Abdullatif; Al Kuwari, Einas; Coyle, Peter; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Rahim, Hanan F Abdul; Yassine, Hadi M; Al Kuwari, Mohamed G; Qotba, Hamda; Al Romaihi, Hamad Eid; Tang, Patrick; Bertollini, Roberto; Al-Thani, Mohamed H; Althani, Asmaa A; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2021 , Article)Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ... -
Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
Ismail, Ahmed; Shurrab, Farah M; Al-Jighefee, Hadeel T; Al-Sadeq, Duaa W; Qotba, Hamda; Al-Shaar, Ibrahim Abdu; Yassine, Hadi M; Abu-Raddad, Laith J; Nasrallah, Gheyath K... more authors ... less authors ( IMR , 2021 , Article)Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ... -
COVID-19 Vaccination: The Mainspring of Challenges and the Seed of Remonstrance
Najjar, Hoda; Al-Jighefee, Hadeel T.; Qush, Abeer; Ahmed, Muna N.; Awwad, Sara; Kamareddine, Layla... more authors ... less authors ( MDPI , 2021 , Article Review)As of March 2020, the time when the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a pandemic, our existence has been threatened and the lives of ... -
Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; Dargham, Soha R.; Al-Dewik, Nader; Qotba, Hamda; Syed, Mohamed; Alnuaimi, Ahmed; Yassine, Hadi M.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2020 , Article)Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ... -
Epidemiology of SARS-CoV2 in Qatar's primary care population aged 10 years and above
Syed, Mohamed Ahmed; Al Nuaimi, Ahmed Sameer; A/Qotba, Hamda Abdulla; Nasrallah, Gheyath K; Althani, Asmaa A; Yassine, Hadi M; Zainel, Abduljaleel Abdullatif; Khudadad, Hanan; Marji, Tamara; Veettil, Shajitha Thekke; Al-Jighefee, Hadeel T; Younes, Salma; Shurrab, Farah; Al-Sadeq, Duaa W; AlFehaidi, Al Anoud Saleh; Yfakhroo, Ameena Ibrahim; AlMesaifri, Meshal Abdulla; Al Mujalli, Hanan; Al Abdulla, Samya Ahmad; Al Kuwari, Mohamed Ghaith; Azad, Faruk Mohammed; Al Malki, Badria Ali Mohamed; Abdulmalik, Mariam Ali... more authors ... less authors ( BMC , 2021 , Article)There is an urgent need to elucidate the epidemiology of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and characterize its potential impact. Investing in characterising the SARS-CoV2 will help plan and ... -
Evaluation of antibody response in symptomatic and asymptomatic covid-19 patients and diagnostic assessment of new IgM/IgG elisa kits
Al-Jighefee, Hadeel T.; Yassine, Hadi M.; Nasrallah, Gheyath K. ( MDPI , 2021 , Article)© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This study aims to study the immune response and evaluate the performances of four new IgM and five IgG enzyme-linked immunosorbent assay (ELISA) kits for detecting ... -
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
Hadi M., Yassine; Al-Jighefee, Hadeel; Al-Sadeq, Duaa W.; Dargham, Soha R.; Younes, Salma N.; Shurrab, Farah; Marei, Reham M.; Hssain, Ali Ait; Taleb, Sara; Alhussain, Hashim A.; Al-Nesf, Maryiam A.; Al-Khal, Abdullatif; Qotba, Hamda; Althani, Asmaa A.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( Elsevier , 2020 , Article)ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ... -
Soluble ACE2 and Angiotensin II levels Modulated in Hypertensive COVID-19 Patients treated with different Antihypertension Drugs
Yalcin, Huseyin C.; Elrayess, Mohamed A; Al-Jighefee, Hadeel T; Al-Ruweidi, Mahmoud Khatib A. A.; Almuraikhy, Shamma; Yassine, Hadi M.... more authors ... less authors ( Qatar University Press , 2021 , Poster)Hypertension is a major risk factor and common comorbidity among severe Coronavirus Disease 2019 (COVID-19) patients. Prominent antihypertensive drugs, such as angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin ...