عرض بسيط للتسجيلة

المؤلفDana, Elkhalifa
المؤلفRayan, Menatallah
المؤلفNegmeldin, Ahmed T.
المؤلفElhissi, Abdelbary
المؤلفKhalil, Ashraf
تاريخ الإتاحة2022-10-24T09:23:02Z
تاريخ النشر2022-01
اسم المنشورBiomedicine & Pharmacotherapy
المعرّفhttp://dx.doi.org/10.1016/j.biopha.2021.112385
الاقتباسElkhalifa, D., Rayan, M., Negmeldin, A. T., Elhissi, A., & Khalil, A. (2022). Chemically modified mRNA beyond COVID-19: potential preventive and therapeutic applications for targeting chronic diseases. Biomedicine & Pharmacotherapy, 145, 112385.
الرقم المعياري الدولي للكتاب0753-3322
معرّف المصادر الموحدhttps://www.sciencedirect.com/science/article/pii/S0753332221011690
معرّف المصادر الموحدhttp://hdl.handle.net/10576/35364
الملخصChemically modified mRNA represents a unique, efficient, and straightforward approach to produce a class of biopharmaceutical agents. It has been already approved as a vaccination-based method for targeting SARS-CoV-2 virus. The COVID-19 pandemic has highlighted the prospect of synthetic modified mRNA to efficiently and safely combat various diseases. Recently, various optimization advances have been adopted to overcome the limitations associated with conventional gene therapeutics leading to wide-ranging applications in different disease conditions. This review sheds light on emerging directions of chemically modified mRNAs to prevent and treat widespread chronic diseases, including metabolic disorders, cancer vaccination and immunotherapy, musculoskeletal disorders, respiratory conditions, cardiovascular diseases, and liver diseases.
راعي المشروعQatar University (Grant # QUCG-CPH-20/21-4 and QUCG-CPH-21/22-1)
اللغةen
الناشرElsevier
الموضوعChemically Modified mRNA
COVID-19
Vaccination
Chronic diseases
Cancer
Diabetes
العنوانChemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases
النوعArticle Review
رقم المجلد145
Open Access user License http://creativecommons.org/licenses/by/4.0/
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة