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AuthorIftikhar, N.
AuthorIftikhar, Neelam
AuthorChatha, Shahzad Ali Shahid
AuthorAhmad, Tanveer
AuthorAli, Qasim
AuthorHussain, Abdullah Ijaz
AuthorRathore, Hassaan Anwer
Available date2022-10-24T10:11:50Z
Publication Date2022
Publication NameCombinatorial Chemistry and High Throughput Screening
Identifierhttp://dx.doi.org/10.2174/1386207325666210923120957
CitationIftikhar, N., Chatha, S. A., Ahmad, T., Ali, Q., Hussain, A. I., & Rathore, H. A. (2022). Fagonia arabica L.: A Review of its Phytochemistry, Pharmacology and Traditional Uses. Combinatorial Chemistry & High Throughput Screening, 25(7), 1187-1199.
ISSN1386-2073
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85130785352&origin=inward
URIhttp://hdl.handle.net/10576/35387
AbstractBackground: Fagonia arabica, belonging to family Zygophyllaceae, is a medicinal plant widely distributed in the desert areas of the world, including Saudi Arabia, Pakistan, India and South Africa. The present review aims to explore the published information on the traditional uses, ethnobotanical knowledge, phytochemistry and various biological activities like antioxidant, antimicrobial, thrombolytic activities and anticoagulant effects of Fagonia arabica with critical analysis on the gaps and future perspectives. Method: A literature survey was performed by searching the digital libraries and the scientific databases including Scopus, Google Scholar, SciFinder, ACS, Web of Science and published books. Results: Fagonia arabica plant has been reported to have a wide range of traditional uses in sore mouth, smallpox, hematological, neurological, endocrinological, inflammatory, cooling agent in stomatitis, vertigo and endothermic reaction in the body. Several bioactive constituents, including glycosides, flavonoids, terpenoids, saponins, alkaloids and trace elements, were recorded from Fagonia arabica plant. The isolation and identification of two flavonoid glycosides (kaempferol-7O-rhamnoside and acacetin-7-O-rhamnoside) were also reported. Fagonia arabica has been studied for its wide range of biological activities, which include antioxidant, antimicrobial, cardioprotective and anticoagulant. Conclusion: It is apparent from the literature that Fagonia arabica plant possesses a wide range of medicinal and pharmacological uses and has been studied for its various pharmacological activities and medicinal applications. Critical analysis reveals that the plant has huge potential for pharmaceutical and pharmacological applications.
Languageen
PublisherBentham Science Publishers
Subjectalkaloids
anticancer
Anticoagulant
antioxidant
cardioprotective
triterpenoid saponins
TitleFagonia arabica L.: A Review of its Phytochemistry, Pharmacology and Traditional Uses
TypeArticle Review
Pagination1187 - 1199
Issue Number7
Volume Number25
ESSN1875-5402
dc.accessType Full Text


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