عرض بسيط للتسجيلة

المؤلفIftikhar, Neelam
المؤلفHussain, Abdullah Ijaz
المؤلفChatha, Shahzad Ali Shahid
المؤلفSultana, Nazia
المؤلفRathore, Hassaan Anwer
تاريخ الإتاحة2022-10-24T10:27:13Z
تاريخ النشر2022-03-01
اسم المنشورFood Science and Nutrition
المعرّفhttp://dx.doi.org/10.1002/fsn3.2695
الاقتباسIftikhar, N., Hussain, A. I., Chatha, S. A. S., Sultana, N., & Rathore, H. A. (2022). Effects of polyphenol- rich traditional herbal teas on obesity and oxidative stress in rats fed a high- fat– sugar diet. Food Science & Nutrition, 10, 698– 711. https://doi.org/10.1002/fsn3.2695
الرقم المعياري الدولي للكتاب2048-7177
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85122880645&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/35390
الملخصHibiscus rosa-sinensis and Zingiber officinalis teas are traditionally used for the therapies of various diseases, including obesity. The present research work was planned to appraise the potential of polyphenol-rich extracts of selected herbal plants in obesity and related biochemical parameters of high-fat–sugar diet-induced obese rats. Three herbal teas were prepared from Hibiscus rosa-sinensis flowers and Zingiber officinalis rhizomes and their mixture (3:1, respectively). Total phenolic contents (TPC) of Hibiscus rosa-sinensis and Zingiber officinalis extracts were found to be 5.82 and 1.45 mg/g of dry plant material, measured as GAE, while total flavonoid contents (TFC) were 9.17 and 1.95 mg/g of dry plant material, measured as CE, respectively. Two doses (250 and 500 mg/kg BW) of each tea were administered and body weight, BMI, kidney, liver, and atherogenic indices, TC, TG, HDL, LDL, VLDL, BT, AST, ALT, AP, SC, MDA, SOD, GSH, and TAC of rats groups were measured. Data showed that higher doses of Hibiscus rosa-sinensis significantly reduced the rat's BMI (0.50 g/cm2) in comparison with the high-fat–sugar diet group (0.79 g/cm2). All treatment groups, especially H-500 group, showed a significant decrease in the elevated kidney and liver weights and atherogenic index in comparison with HFSDC groups. Higher doses of Hibiscus rosa-sinensis significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. A significant decrease in the levels of serum TC, TG, LDL, and VLDL was observed in all the treatment groups in comparison with the HFSDC group. Furthermore, all the teas, especially higher doses of Hibiscus rosa-sinensis, prevented the alterations in MDA, SOD, and GSH levels of experimental groups, thus showing the potential against oxidative stress. It can be concluded from these results that Hibiscus rosa-sinensis teas exhibited strong protective effects against obesity and oxidative stress, especially at higher doses.
اللغةen
الناشرJohn Wiley & Sons, Ltd.
الموضوعBMI
GSH
high-fat diet
kidney index
LDL and HDL
liver index
MDA
nutraceutical
phenolic acids and flavonoids
SOD
العنوانEffects of polyphenol-rich traditional herbal teas on obesity and oxidative stress in rats fed a high-fat–sugar diet
النوعArticle
الصفحات698– 711
رقم العدد3
رقم المجلد10
ESSN2048-7177
dc.accessType Open Access


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة