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المؤلفVippadapu, Prasanna
المؤلفGillani, Syed Wasif
المؤلفThomas, Dixon
المؤلفAhmed, Fiaz
المؤلفGulam, Shabaz Mohiuddin
المؤلفMahmood, Rana Kamran
المؤلفMenon, Vineetha
المؤلفAbdi, Semira
المؤلفRathore, Hassaan Anwer
تاريخ الإتاحة2022-10-25T06:41:00Z
تاريخ النشر2022-04
اسم المنشورFrontiers in Pharmacology
المعرّفhttp://dx.doi.org/10.3389/fphar.2022.849044
الاقتباسVippadapu P, Gillani SW, Thomas D, Ahmed F, Gulam SM, Mahmood RK, Menon V, Abdi S and Rathore HA (2022) Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital. Front. Pharmacol. 13:849044. doi: 10.3389/fphar.2022.849044
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85128816527&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/35398
الملخصBackground: This study was aimed to describe the choice of Surgical Antimicrobial Prophylaxis at a tertiary-level care hospital in United Arab Emirates. It also associated the choice between two leading antimicrobials for the SAP to the site of surgery. Methods: A descriptive drug use evaluation was performed retrospectively to study choices of antimicrobials in surgical antibiotic prophylaxis. An analytical cross-sectional study design was used to develop a hypothesis regarding the choice of ceftriaxone. Data were collected from the medical records of Hospital from July 2020 to December 2020. Results were presented in numbers and percentages. Results: SAP data were collected from 199 patients, of which 159 were clean or clean-contaminated. Dirty surgeries (18) needed a higher level of antimicrobials as there were infections to be treated. For other surgeries with no infection, overuse of antimicrobials was found regarding the choice of antimicrobials. Surgical antibiotic Prophylaxis was administered within the recommended time prior to surgeries. Ceftriaxone was preferred over cefuroxime in all types of surgeries based on the timing of Surgical Antibiotic Prophylaxis, wound classification, and the surgical site. A statistically significant association for choice of ceftriaxone over cefuroxime was found regarding surgical sites (p-value <0.05). About 99% of the patients were prescribed discharge antimicrobials when 158 (80%) surgeries were clean or clean-contaminated. Conclusion: Overuse of antimicrobials was found in surgical antimicrobial prophylaxis. Ceftriaxone was preferred more than cefuroxime in all types of surgeries. No surgical site infections were reported. A follow-up comparative study is recommended to decrease antimicrobial use without increasing risk of surgical site infection.
اللغةen
الناشرFrontiers Media
الموضوعantimicrobial stewardship
cefotaxime
ceftriaxone
surgeries
surgical antimicrobial prophylaxis
surgical site infections
العنوانChoice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital
النوعArticle
الصفحات1-9
رقم المجلد13
ESSN1663-9812
dc.accessType Open Access


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