بحث بسيط
السجلات المعروضة 1 -- 10 من 12
Investigating the effect of hyperglycemia on embryonic heart development using the chick embryo model
(
Qatar University Press
, 2020 , Poster)
Congenital heart defects (CHDs) represent the most common form of human birth defects. Maternal diabetes increases the risk of CHD by 3-5 folds. During heart development, little is known about the effects of high blood ...
Assessment of Metal Organic Framework as Potential Drug Carriers in Cardiovascular Diseases
(
Qatar University Press
, 2020 , Poster)
Background: Cardiovascular diseases (CVDs) are considered the major cause of death worldwide. Therapeutic delivery to the cardiovascular system may play an important role in the successful treatment of a variety of CVDs, ...
The influence of shear stress on nanomaterial's uptake by MDA-231 breast cancer cells
(
Qatar University Press
, 2020 , Poster)
Introduction: Recently, nanotechnology products have been used for a variety of applications including the medical field. Two dimensional (2D) nanomaterials have attracted a growing interest due to its unique properties ...
Toxicity assessment of treated sewage effluent using the zebrafish embryo model
(
Qatar University Press
, 2020 , Poster)
Background: In a context of tremendous economic value, the management and protection of water resources in Qatar has long been a significant issue as part of the global wastewater management plan. The process is based on ...
Unraveling Gene Expression Profiles of Cardiac Genes That Participate in Embryonic Development of Congenital Heart Defects Using Chick Embryo
(
Qatar University Press
, 2020 , Poster)
Hypoplastic left heart syndrome (HLHS) is a rare but serious subtype of congenital heart defects (CHDs) at which the hemodynamics are disturbed. In this project, HLHS was introduced surgically by left atrial ligation (LAL) ...
Investigating the Cardiac Effects of New Generation Anti-Diabetic Drug EmpagliflozinUsing Zebrafish Embryo Model
(
Qatar University Press
, 2020 , Poster)
Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of anti-diabetic drugs focuses on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism ...
In Vivo Investigation of Cardiac Benefits of Sodium Glucose Cotransporter Inhibition Using the Zebrafish Model
(
Qatar University Press
, 2020 , Poster)
Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of antidiabetic drugs focuses on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism ...
Investigating the efficacy of natural blood glucose lowering compounds in the prevention of congenital heart defects during maternal diabetes using the chick embryo
(
Qatar University Press
, 2020 , Poster)
Diabetes is a metabolic disorder that is characterized by hyperglycemia. Although there are several drugs available for diabetes, patients tend to follow natural remedies. However, the use of these natural remedies lacks ...
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
(
Qatar University Press
, 2021 , Poster)
Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ...
Direct Measurement of Vessel Pressure in Chicken Embryo during Development
(
Qatar University Press
, 2021 , Poster)
Hemodynamic conditions play a critical role in embryonic cardiovascular development, and altered blood flow leads to congenital heart defects (CHD). Chicken embryos are commonly used as models of cardiac development, with ...