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Blue Laser Light Counteracts HSV-1 in the SH-SY5Y Neuronal Cell Model of Infection
(
MDPI
, 2022 , Other)
Herpes simplex virus 1 (HSV-1) is wide-spread virus that triggers painful and recurrent infections, as herpes labialis, causing blister lesions on the lip. HSV-1 infection can be a lifelong condition starting from childhood ...
SARS-CoV-2 Short-Time Infection Produces Relevant Cytopathic Effects in Vero E6 Cell Line.
(
MDPI
, 2021 , Article)
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets from positive subjects to susceptible hosts or by direct contact with an infected individual. Our study ...
Advanced photodynamic therapy with an engineered M13 phage targeting EGFR: Mitochondrial localization and autophagy induction in ovarian cancer cell lines
(
Elsevier
, 2022 , Article)
Photodynamic therapy (PDT) is a potential synergistic approach to chemotherapy for treating ovarian cancer, the most lethal gynecologic malignancy. Here we used M13 bacteriophage as a targeted vector for the efficient ...
Pleiotropic role of notch signaling in human skin diseases
(
MDPI
, 2020 , Article Review)
Notch signaling orchestrates the regulation of cell proliferation, differentiation, migration and apoptosis of epidermal cells by strictly interacting with other cellular pathways. Any disruption of Notch signaling, either ...
Plant Antimicrobial Peptides as Potential Tool for Topic Treatment of Hidradenitis Suppurativa
(
Frontiers Media
, 2021 , Article)
Among chronic skin autoinflammatory diseases, Hidradenitis Suppurativa (HS) stands out for its chronicity, highly variable condition, and profound impact on the patients’ quality of life. HS is characterized by suppurative ...
Strategies and Perspectives for UV Resonance Raman Applicability in Clinical Analyses of Human Sperm RNA.
(
MDPI
, 2021 , Article)
Developing a deeper knowledge about the impact of DNA and RNA epigenetic mutations on sperm production and fertilization performance is essential for selecting best quality samples in Assisted Reproductive Technologies ...
Hiv-1 infection transcriptomics: Meta-analysis of cd4+ t cells gene expression profiles
(
MDPI
, 2021 , Article Review)
HIV-1 infection elicits a complex dynamic of the expression various host genes. High throughput sequencing added an expressive amount of information regarding HIV-1 infections and pathogenesis. RNA sequencing (RNA-Seq) is ...
Neck circumference predicts mortality in hospitalized COVID-19 patients
(
MDPI
, 2021 , Article)
We aimed to determine whether neck circumference predicts mortality among hospitalized COVID-19 patients with respiratory failure. We performed a prospective multicenter (Italy and Brasil) study carried out from March to ...
25-Hydroxyvitamin D serum levels inversely correlate to disease severity and serum C-reactive protein levels in patients with hidradenitis suppurativa
(
Wiley
, 2021 , Other)
Vitamin D exerts functions in skin physiology by modulating keratinocyte proliferation and different immunoregulatory processes.1 In several dermatoses, vitamin D correlates to disease severity and is significantly lower ...
Proteomic study identifies glycolytic and inflammation pathways involved in recurrent otitis media
(
MDPI
, 2020 , Article)
Recurrent acute otitis media (RAOM) in children is clinically defined as the occurrence of at least three episodes of acute otitis media over a course of 6 months. A further common pathological condition of interest in the ...