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Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
(
Elsevier
, 2021 , Article)
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ...
Natural resorcylic acid lactones: A chemical biology approach for anticancer activity
(
Elsevier
, 2022 , Article)
Resorcylic acid lactones (RALs) are fungal polyketides that consist of a β-resorcylic acid residue (2,4-dihydroxybenzoic acid) embedded in a macrolactone ring. RALs exhibit a broad range of biological activities, including ...
Early Graft Failure After Living-Donor Liver Transplant
(
Springer Nature
, 2024 , Article)
Background: Living-donor liver transplantation (LDLT) has been increasing in the USA. While data exist on longer-term patient and graft outcomes, a contemporary analysis of short-term outcomes is needed. Aim: Evaluate ...
The impact of COVID-19 on the mental health of Lebanese pharmacists: A national cross-sectional study
(
Frontiers Media S.A.
, 2023 , Article)
Introduction: The COVID-19 pandemic has induced a global mental health crisis with variable consequences. This study aimed to assess the psychological impact of COVID-19 regarding anxiety, insomnia, depression, and response ...
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
(
Elsevier
, 2022 , Article)
Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by ...
Predictors for hospital admission in emergency department patients with benign paroxysmal positional vertigo: A retrospective review.
(
Public Library of Science
, 2023 , Article)
This study aims to assess the incidence of Emergency Department (ED) visits for benign paroxysmal positional vertigo (BPPV), describe patient characteristics, management practices and predictors of inpatient admission of ...
Potassium Ion Channels in Glioma: From Basic Knowledge into Therapeutic Applications
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Ion channels, specifically those controlling the flux of potassium across cell membranes, have recently been shown to exhibit an important role in the pathophysiology of glioma, the most common primary central nervous ...
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
(
Elsevier
, 2021 , Article)
Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. Owing to ...
Ovarian torsion: A retrospective case series at a tertiary care center emergency department
(
Public Library of Science
, 2024 , Article)
Ovarian torsion (OT) is a gynecological emergency that can have diverse clinical presentations makings its diagnosis especially challenging. Few studies exist in the literature describing the clinical presentation as well ...
Dietary Intake Is Not Associated with Body Composition nor with Biochemical Tests but with Psychological Status of Cancer Patients Receiving Chemotherapy
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Chemotherapy can negatively affect cancer patients’ eating patterns, psychological status, body composition, and quality of life. In this study, we aimed to investigate the correlations between dietary intake/care and the ...