Show simple item record

AuthorIbrahim, Ayman R.
AuthorElgamal, Mohamed E.
AuthorMoursi, Moaz O.
AuthorShraim, Bara A.
AuthorShraim, Muath A.
AuthorShraim, Mujahed
AuthorAl-Omari, Basem
Available date2023-02-19T09:13:15Z
Publication Date2022-10-01
Publication NameInternational Journal of Environmental Research and Public Health
Identifierhttp://dx.doi.org/10.3390/ijerph191912114
CitationIbrahim, A.R.; Elgamal, M.E.; Moursi, M.O.; Shraim, B.A.; Shraim, M.A.; Shraim, M.; Al-Omari, B. The Association between Early Opioids Prescribing and the Length of Disability in Acute Lower Back Pain: A Systematic Review and Narrative Synthesis. Int. J. Environ. Res. Public Health 2022, 19, 12114. https://doi.org/10.3390/ijerph191912114
ISSN16617827
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85139813085&origin=inward
URIhttp://hdl.handle.net/10576/40132
AbstractBackground: There is conflicting evidence with respect to whether early opioid prescribing (EOP) within the first two weeks of acute Low Back Pain (LBP) onset is associated with the length of disability (LOD). The aim of this systematic review was to examine the relationship between EOP and LOD in individuals with acute LBP. Methods: A systematic search of Medline, EMBASE, and CINAHL was conducted. The Newcastle–Ottawa scale was used to assess the methodological quality of included studies. A narrative synthesis of findings was used owing to between-study heterogeneity. Results: Six cohort studies using workers’ compensation administrative data on 178,130 adults with LBP were included. Most studies were of good methodological quality. One study reported that LBP cases with EOP had higher LOD by 4 days than cases without EOP. Two studies reported that each 100 mg morphine equivalent amount (MEA) was associated with an increase in mean LOD by 0.4 day (95% confidence interval (CI): 0.3, 0.5) and 0.4 day (95% CI: 0.3, 0.4). One study showed that LBP cases with EOP had a higher hazard of continuation of time loss benefits by 1.94 (95% CI 1.86, 2.02). One study reported a dose–response relationship between MEA of EOP and LOD ranging between 5.2 days (95% CI 14.6, 25.0) for 1–140 mg MEA and 69.1 (95% CI 49.3, 89.0) for 450+ mg MEA. One study reported that LBP cases with EOP had a higher mean LOD by 3.8 days, but there was no statistically significant relationship between EOP and LOD (Hazard ratio 1.02; 95% CI 0.91, 1.13). Conclusions: The use of early opioid in the management of acute uncomplicated LBP is associated with prolonged disability duration. Further research on factors influencing inadequate adherence to evidence-based guidelines and optimal strategies to modify such factors may improve disability outcomes among patients presenting with acute LBP.
Languageen
PublisherMDPI
Subjectlength of disability
low back pain
opiates
opioids
return to work
sick leave
systematic review
TitleThe Association between Early Opioids Prescribing and the Length of Disability in Acute Lower Back Pain: A Systematic Review and Narrative Synthesis
TypeArticle Review
Issue Number19
Volume Number19
dc.accessType Open Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record