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AuthorMohamed, Nura Adam
AuthorZupin, Luisa
AuthorMazi, Sarah Ismail
AuthorAl-Khatib, Hebah A
AuthorCrovella, Sergio
Available date2023-03-12T06:28:30Z
Publication Date2023-02-13
Publication NameVaccines
Identifierhttp://dx.doi.org/10.3390/vaccines11020428
CitationMohamed, N.A.; Zupin, L.; Mazi, S.I.; Al-Khatib, H.A.; Crovella, S. Nanomedicine as a Potential Tool against Monkeypox. Vaccines 2023, 11, 428. https://doi.org/10.3390/vaccines11020428
URIhttp://hdl.handle.net/10576/40926
AbstractHuman monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and self-limiting; however, recent worldwide reports of several cases suggest otherwise. Especially with monkeypox being recognized as the most important orthopoxvirus infection in humans in the smallpox post-eradication era, its spread across the globe marks a new epidemic. Currently, there is no proven treatment for human monkeypox, and questions about the necessity of developing a vaccine persist. Notably, if we are to take lessons from the COVID-19 pandemic, developing a nanomedicine-based preventative strategy might be prudent, particularly with the rapid growth of the use of nanotechnology and nanomaterials in medical research. Unfortunately, the collected data in this area is limited, dispersed, and often incomplete. Therefore, this review aims to trace all reported nanomedicine approaches made in the monkeypox area and to suggest possible directions that could be further investigated to develop a counteractive strategy against emerging and existing viruses that could diminish this epidemic and prevent it from becoming a potential pandemic, especially with the world still recovering from the COVID-19 pandemic.
SponsorNAM is a recipient of the Early Career Research Award (ECRA; ECRA03-006-3-004) from the Qatar National Research Fund (QNRF), and the L’Oréal-UNESCO for Women in Science Middle East Regional Young Talents ward 2021. This work was supported by the Ministry of Health, Rome-Italy, in collaboration with the Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste–Italy (RC 47/20).
Languageen
PublisherMDPI
Subjectmonkeypox
nanomedicine
vaccine
TitleNanomedicine as a Potential Tool against Monkeypox.
TypeArticle Review
Issue Number2
Volume Number11
ESSN2076-393X
dc.accessType Open Access


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