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Medicine Research [1762 items ]
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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
( Elsevier , 2025 , Article)BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, ... -
In-Hospital Outcomes and Temporal Trends of Surgical Versus Intravascular Ultrasound–Guided Endovascular Interventions for Femoropopliteal Disease
( Elsevier , 2025 , Article)BackgroundPeripheral artery disease is a global health concern, with femoropopliteal disease being a common manifestation. Recent advancements in endovascular interventions (EVI), guided by intravascular ultrasound (IVUS), ... -
Intracranial extension of parotid adenoid cystic carcinoma presenting as trigeminal neuralgia: A case report
( Elsevier , 2025 , Article)Being rare malignancies, parotid gland adenocarcinomas are most significantly represented by the ACC subtype due to their aggressive nature and propensity for PNI. We present a case of a 56-year-old male with right-sided ... -
Long-term changes in lipid indices following Roux-en-Y gastric bypass: a meta-analysis
( Springer , 2025 , Article)Introduction: Bariatric surgery yields clinically significant long-term weight loss accompanied by marked improvements in numerous weight-related comorbidities including type 2 diabetes, hypertension, dyslipidemia, obstructive ... -
Rhus coriaria (Sumac) induces autophagic cell death and inhibits mTOR, p38MAPK and STAT3 pathways in 5fluorouracil-resistant colorectal cancer cells
( Frontiers Media , 2025 , Article)Introduction: Colorectal cancer is a leading cause of cancer related-death worldwide, and resistance to 5-fluorouracil (5FU, a key component of chemotherapy regimens, is a major clinical concern. We have previously elucidated ... -
Predictive performance of noninvasive factors for liver fibrosis in severe obesity: a screening based on machine learning models
( Springer , 2025 , Article)Objectives: Liver fibrosis resulting from nonalcoholic fatty liver disease (NAFLD) and metabolic disorders is highly prevalent in patients with severe obesity and poses a significant health challenge. However, there is a ... -
Revolutionizing hypertension treatment: aprocitentan’s dual action against resistant hypertension
( Taylor and Francis Group , 2025 , Article)Hypertension (HTN) significantly contributes to worldwide morbidity and mortality [Citation1,Citation2]. It impacts around 1.3 billion individuals globally, rendering it one of the most prevalent cardiovascular diseases ... -
Liver Transplantation for Non-hepatocellular Carcinoma: The Role of Immune Checkpoint Inhibitors
( Elsevier , 2025 , Article Review)Colorectal cancer (CRC), gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN), and cholangiocarcinoma (CCA) exhibit high rates of morbidity and mortality once metastasized to the liver. Liver transplantation (LT) is a ... -
Pharmacological Frontiers: The Rise of Selective NaV1.8 Inhibition for Pain Management
( Springer , 2025 , Article)Pain is a multifaceted disorder encompassing sensory, emotional, and cognitive dimensions. It presents a ubiquitous challenge to human health and well-being, demanding effective and safe management strategies [1]. Various ... -
Impact of pomegranate juice consumption on glycemic indices: a systematic review and meta-analysis
( Emerald Publishing , 2025 , Article)Purpose: The purpose of this meta-analysis was to examine the effect of pomegranate juice (PJ) intake on glycemic control in adults. Design/methodology/approach: Materials and methods: PubMed (Medline), ISI Web of Science, ... -
Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
( Elsevier , 2024 , Article)Viral malignancies represent a distinct entity among cancers. Oncoviruses like the Human Papilloma Virus (HPV) and the Epstein Barr Virus (EBV) are highly potent inducers of oncogenic transformation leading to tumor ... -
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
( Springer , 2025 , Article)Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. Gold (AuNPs) and silver (AgNPs) NPs are among ... -
Incidental finding of hepatic pseudolesion from aberrant right gastric vein in a breast cancer patient
( Elsevier , 2025 , Article)Aberrant right gastric veins (ARGV) represent rare anatomical variations that can result in hepatic pseudolesions, mimicking malignancies due to their atypical drainage directly into the liver parenchyma. This case highlights ... -
Corrigendum to “Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy” [Cancer Lett. 607 (2024) 217318]
( Elsevier , 2025 , Article)The author acknowledges with regret that the source of funding for open access publishing was not initially credited. The details are provided below: Acknowledgement Open Access funding was provided by the Qatar National ... -
Peripartum Hemorrhage: Recent Updates in Management
( Springer Nature , 2024 , Book chapter)Peripartum hemorrhage, which can occur during pregnancy, labor, or delivery, is an all-inclusive term for bleeding that can happen from 24+0 weeks of gestation to 12 weeks after birth. It is a serious obstetric emergency ... -
Fetal Tele-Echocardiography-An Approach to Improving Diagnosis and Management
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Introduction: Antenatal diagnosis of cardiac abnormalities and counselling parents about postnatal care require a multidisciplinary team, which includes a paediatric cardiologist, a neonatologist, and a fetal medicine ... -
Characterization of blaNDM in two Escherichia coli ST1193 clinical isolates in the Gulf region
( Oxford University Press , 2024 , Article)Introduction: Escherichia coli ST1193 is an emerging high-risk clone associated with the production of plasmid-mediated CTX-type extended-spectrum β-lactamases. However, this clone has seldom been found to contain plasmids ... -
Congenital and Perinatal Viral Infections: Consequences for the Mother and Fetus
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article Review)Viruses are the most common congenital infections in humans and an important cause of foetal malformations, neonatal morbidity, and mortality. The effects of these infections, which are transmitted in utero (transplacentally), ... -
Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis
( BioMed Central Ltd , 2024 , Article)Background: Pathogenesis of atherosclerosis is largely mediated by inflammatory process. Statins are lipid-lowering drugs which also have anti-inflammatory effects. 18 fluorine radiolabeled fluorodeoxyglucose (18 F-FDG) ... -
Health and Well-Being in the Context of Health-Promoting University Initiatives: Protocol for a Mixed Methods Needs Assessment Study at Qatar University
( JMIR Publications Inc. , 2024 , Article)Background: Health-promoting universities are dedicated to fostering learning environments and organizational cultures that support the physical and mental well-being of students, faculty, and staff. As students constitute ...
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