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Medicine Research [2051 items ]
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Global disparities in adrenaline access: A World Allergy Organization call for equity in anaphylaxis care
( Elsevier , 2025 , Article)Anaphylaxis is a medical emergency and can be fatal if not treated immediately.1,2 Adrenaline remains the only effective first-line treatment capable of reversing anaphylaxis in all settings, including in the community,1,2 ... -
Hybrid Neural Networks for Precise Hydronephrosis Classification Using Deep Learning
( Elsevier , 2025 , Article)ObjectiveTo develop and evaluate a deep learning framework for automatic kidney and fluid segmentation in renal ultrasound images, aiming to enhance diagnostic accuracy and reduce variability in hydronephrosis assessment. ... -
Low-Intensity Ultrasound and Neural Repair: Unlocking Brain Plasticity and Functional Recovery
( Elsevier , 2026 , Article Review)Emerging evidence highlights the potential of transcranial focused ultrasound in enhancing brain function and repair. Low-intensity focused ultrasound (LIFUS) enables precise, non-invasive modulation of neuronal activity, ... -
Dual COX/5-LOX inhibition by isorhamnetin-3-O-glucoside from Anthyllis cytisoides: An integrated chemical-enzymatic-computational study
( Elsevier , 2026 , Article)Ethnopharmacological relevanceAnthyllis cytisoides L. is a forage shrub native to the western Mediterranean basin, traditionally used in folk medicine to treat respiratory and gastrointestinal inflammation. However, its ... -
The role of small, dense lipoproteins in type-2 diabetes and maturity-onset diabetes of the young (MODY): What's new
( Elsevier , 2025 , Article)Although diabetic dyslipidemia is a well-known and extensively studied phenomenon, its features continue to attract significant attention from both researchers and clinicians. Given that lipid profile abnormalities are ... -
Liposomal delivery of DK14 chalcone analogue: A promising therapeutic strategy against triple-negative breast cancer
( Elsevier , 2026 , Article)Triple negative breast cancer (TNBC) is considered the most aggressive type of breast malignancy. TNBC management approaches remain limited, with a high risk of relapse and metastasis. Chalcone compounds are established ... -
A novel virtual patient approach for cross-patient multimodal fusion in enhanced breast cancer detection
( Elsevier , 2026 , Article)Multimodal medical imaging combining conventional imaging modalities such as mammography, ultrasound, and histopathology has shown significant promise for improving breast cancer detection accuracy. However, clinical ... -
Correction: Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer (PLoS One (2014) 9:10 (e109630) DOI: 10.1371/journal.pone.0109630)
( Public Library of Science (PLOS) , 2025 , Article)There are errors in Figs 3 and 8. Specifically, • In Fig 3A, the Early Apop. values reported in the lower right quadrants of the Control, 50 µM, and 100 µM panels are incorrect. A corrected Fig 3 is provided with this ... -
The Promise of Exosomes in Cardiac Repair: When ‘Best Things Come in Small Packages’
( John Wiley and Sons Inc , 2025 , Article)Myocardial ischaemia continues to be a predominant global cause of mortality, leaving survivors with compromised quality of life and significant loss of functional cardiomyocytes. The main therapeutic approach, which ... -
Rare presentation of lues maligna and nodular syphilis in an immunocompetent patient
( Elsevier , 2026 , Report)Secondary syphilis can present in many ways; common presentations of secondary syphilis include a generalized papulosquamous or pitriasifrom generalized eruption that commonly affects the palms and soles.1 Recently, a rapid ... -
7-O-methylpunctatin is a potential inhibitor of human arachidonate 5-lipoxygenase: molecular and structural insights into anti-atherosclerosis therapeutics
( Springer Nature , 2026 , Article)We have recently demonstrated that 7-O-methylpunctatin (MP), a novel homoisoflavonoid, suppresses inflammation-induced arterial pathogenesis. However, the precise biochemical mechanisms underlying its atheroprotective ... -
Reduced appetite after body contouring is associated with low glucose-dependent insulinotropic polypeptide levels
( Elsevier , 2025 , Article)Gut hormone modulation is central to appetite regulation following bariatric surgery, but its relevance among individuals undergoing body contouring procedures, with or without bariatric surgery, remains unclear. In this ... -
Severe Blepharokeratoconjunctivitis in Children—The Toronto Experience
( Elsevier , 2026 , Article)PurposeTo report on the clinical characteristics and treatment outcomes of a large cohort of pediatric patients who presented with severe blepharokeratoconjunctivitis (BKC). DesignRetrospective consecutive cohort study. ... -
Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023
( Elsevier , 2025 , Article)Comprehensive, comparable, and timely estimates of demographic metrics—including life expectancy and age-specific mortality—are essential for evaluating, understanding, and addressing trends in population health. The ... -
Zebrafish: A Versatile and Powerful Model for Biomedical Research
( John Wiley and Sons Inc , 2025 , Article)Zebrafish (Danio rerio) have become a versatile model in precision medicine, bridging fundamental biology with translational applications. Their optical transparency, rapid development, and high genetic conservation with ... -
Reassessing PCI Timing in High Bleeding Risk Patients: Evidence, Strategies, and Outcomes
( John Wiley and Sons Inc , 2025 , Article)Percutaneous coronary intervention (PCI) in patients with high bleeding risk (HBR) presents a therapeutic challenge, requiring careful balancing of ischemic prevention and bleeding avoidance. The Academic Research Consortium ... -
Glycogen-Rich Clear Cell Carcinoma of the Breast: Report of Two New Cases and an Updated Literature Review.
( Sarajevo Akademija nauka i umjetnosti Bosne i Hercegovine , 2025 , Article)To report two additional cases of glycogen-rich clear cell carcinoma (GRCC) of the breast - detailing their clinicopathologic features, immunophenotypes, and follow-up - and to provide an updated literature review since ... -
Challenges Facing Contemporary Pediatric Nephrology: A Call to Global Advocacy.
( The American Society of Nephrology , 2025 , Article)A worldwide paucity of pediatric nephrologists exists, with a median prevalence of 0.69 pediatric nephrologists/million population.1 In a survey of clinicians in 71 countries by the International Pediatric Nephrology ... -
Acute Ischemic Stroke and Myocardial Infarction in a Patient Diagnosed With Infection: A Case Report and a Literature Review.
( Wiley , 2025 , Article)Cholera is an acute diarrheal disease caused by which primarily affects the gastrointestinal system. However, severe dehydration and electrolyte imbalances caused by diarrhea can precipitate systemic complications, including ... -
Evaluating large language models for renal colic imaging recommendations: a comparative analysis of Gemini, copilot, and ChatGPT-4.0
( BioMed Central Ltd , 2025 , Article)Background: The field of natural language processing (NLP) has evolved significantly since its inception in the 1950s, with large language models (LLMs) now playing a crucial role in addressing medical challenges. Objectives: ...
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