تصفح College of Medicine حسب العنوان
السجلات المعروضة 1247 -- 1266 من 1344
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Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
( American Society for Pharmacology and Experimental Therapy (ASPET) , 2023 , Article)Cardiovascular complications of diabetes and obesity remain a major cause for morbidity and mortality worldwide. Despite significant advances in the pharmacotherapy of metabolic disease, the available approaches do not ... -
This House believes that considering the continuous quarantine and precautionary measures should be of a priority over lifting the restrictions to avoid the negative economic and social consequences
( College of Medicine - Qatar University , 2020 , Video)NA -
Thrombin generation measured on ST Genesia, a new platform in the coagulation routine lab: Assessment of analytical and between-subject variation
( Wiley Open Access , 2022 , Article)Background: The thrombin generation (TG) assay, which measures global coagulation, has mainly been used as a research tool to investigate thrombotic and bleeding disorders. Recently, Diagnostica Stago launched the ST ... -
Thromboinflammatory Processes at the Nexus of Metabolic Dysfunction and Prostate Cancer: The Emerging Role of Periprostatic Adipose Tissue
( MDPI , 2022 , Article)The increased global prevalence of metabolic disorders including obesity, insulin resistance, metabolic syndrome and diabetes is mirrored by an increased incidence of prostate cancer (PCa). Ample evidence suggests that ... -
Thrombosis Management and Challenges in COVID-19 Patients Presenting with Acute Coronary Syndromes.
( Medknow Publications , 2020 , Article)Thrombotic complications in patients with coronavirus disease 2019 (COVID-19) infection have been increasingly recognized, particularly those affecting the cardiovascular system. Patients with COVID-19 infection can suffer ... -
Thromboxane biosynthesis and future events in diabetes: the ASCEND trial
( Oxford University Press , 2024 , Article)Background and Thromboxane (TX) A2, released by activated platelets, plays an important role in atherothrombosis. Urinary 11-dehydro-Aims TXB2 (U-TXM), a stable metabolite reflecting the whole-body TXA2 biosynthesis, is ... -
Thujone inhibits the function of 7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm
( Elsevier Ireland Ltd , 2017 , Article)Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of 7 subunit of the human nicotinic acetylcholine (7 nACh) receptor expressed in Xenopus oocytes using ... -
Time to Move Beyond a Binary Criterion for Gestational Diabetes?
( Springer Nature , 2024 , Article)Over the years, several international guidelines have been developed by specialist organizations for the diagnosis of gestational diabetes mellitus (GDM). However, these guidelines vary and lack consensus on what level of ... -
Titanium Nanorods Loaded PCL Meshes with Enhanced Blood Vessel Formation and Cell Migration for Wound Dressing Applications.
( Wiley , 2019 , Article)Proper management of nonhealing wounds is an imperative clinical challenge. For the effective healing of chronic wounds, suitable wound coverage materials with the capability to accelerate cell migration, cell proliferation, ... -
Total temporomandibular joint replacement prostheses: a systematic review and bias-adjusted meta-analysis
( Elsevier , 2017 , Article)The aim of the present study was to determine which prosthesis has resulted in the best outcomes after total temporomandibular joint replacement (TMJR). A comprehensive electronic search was undertaken in September 2015. ... -
Toward a meta-vaccine future: Promoting vaccine confidence in the metaverse
( SAGE Publications Inc. , 2023 , Article)The metaverse has a promising role to serve as a global platform and tackle one of the most intractable public health challenges; vaccine hesitancy. Active efforts in this field can enhance vaccine acceptance thus leading ... -
Towards a better understanding of self-management interventions in type 2 diabetes: A concept analysis
( Elsevier Ltd , 2022 , Article)Objectives: Diabetes self-management educational (DSME) interventions can vary considerably, and it is unclear what is the operational conceptualization of the ideal delivery to individuals with type 2 diabetes (T2D). ... -
Towards a better understanding of self-management interventions in type 2 diabetes: A meta-regression analysis
( Elsevier Ltd , 2021 , Article)Aims: Attributes that operationally conceptualize diabetes self-management education (DSME) interventions have never been studied previously to assess their impact on relevant outcomes of interest in people with type 2 ... -
Towards Molecular Profiling in Multiple Myeloma: A Literature Review and Early Indications of Its Efficacy for Informing Treatment Strategies.
( MDPI , 2018 , Article)Multiple myeloma (MM), the second most common hematologic malignancy, is characterized by the clonal expansion of plasma cells. Despite dramatic improvements in patients' survival over the past decade due to advances in ... -
Towards the Pharmacological Validation and Phytochemical Profiling of the Decoction and Maceration of Bruguiera gymnorhiza (L.) Lam.-A Traditionally Used Medicinal Halophyte
( MDPI , 2022 , Article)Decoctions (leaves and roots) of Bruguiera gymnorhiza (L.) Lam. are traditionally used against diabetes in many countries, including Mauritius. This study endeavoured to evaluate the inhibitory potential of leaves, roots, ... -
Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials
( Elsevier , 2024 , Article)Study objectiveTraumatic injury causes a significant number of deaths due to bleeding. Tranexamic acid (TXA), an antifibrinolytic agent, can reduce bleeding in traumatic injuries and potentially enhance outcomes. Previous ... -
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ... -
Transethnic Transferability of a Genome-wide Polygenic Score for Coronary Artery Disease.
( American Heart Association , 2020 , Article)N/A -
Transforming growth factor-β1 inhibits interleukin-1β-induced expression of inflammatory genes and Cathepsin S activity in human vascular smooth muscle cells
( John Wiley and Sons Inc , 2021 , Article)Objective and design This study investigated the opposite mechanisms by which IL-1β and TGF-β1 modulated the inflammatory and migratory phenotypes in cultured human intimal vascular smooth muscle cells vSMCs. Materials ... -
Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
( BioMed Central Ltd , 2023 , Article)Background: The mechanism of tumor immune escape and progression in colorectal cancer (CRC) is widely investigated in-vitro to help understand and identify agents that might play a crucial role in response to treatment and ...
