Browsing College of Medicine by Title
Now showing items 1266-1285 of 1337
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Triple therapy with pravastatin, low molecular weight heparin and low dose aspirin improves placental haemodynamics and pregnancy outcomes in obstetric antiphospholipid syndrome in mice and women through a nitric oxide-dependent mechanism
( Elsevier , 2020 , Article)Objectives: A previous pilot study showed that pravastatin supplementation improved pregnancy outcomes in women with obstetric antiphospholipid syndrome (OAPS) that developed placental insufficiency despite standard of ... -
Trop-2 protein as a therapeutic target: A focused review on Trop-2-based antibody-drug conjugates and their predictive biomarkers
( Association of Basic Medical Sciences of FBIH , 2022 , Article)Antibody-drug conjugates represent a new class of highly potent antineoplastic drugs built by attaching a small molecule of an anticancer drug (payload) or another therapeutic agent to an antibody recognizing an epitope ... -
Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group
( Academy of Sciences and Arts of Bosnia and Herzegovina , 2022 , Article)In the present review, we briefly discuss the breakthrough advances in precision medicine using a tumor-agnostic approach and focus on BRAF treatment modalities, the mechanisms of resistance and the diagnostic approach in ... -
Twisting of a Giant Cystic Meckel's Diverticulum in a Toddler: A Case Report and Brief Literature Review
( University Clinical Hospital Tuzla , 2022 , Article)Objective: Herein we report an unusual case of torsed giant cystic Meckel's diverticulum (MD) in a three-year-old boy, il-lustrating the rarity of this condition and briefly reviewing the literature on it. Case Report: A ... -
Typical and atypical carcinoid tumors of the lung: A Clinicopathological correlation of 783 cases with Emphasis on histological features
( Elsevier , 2020 , Article)ABSTRACT We present 783 surgical resections of typical and atypical carcinoid tumors of the lung identified in the pathology files of 20 different pathology departments. All cases were critically reviewed for clinical and ... -
Ultrasound controlled paclitaxel releasing system—A novel method for improving the availability of coronary artery drug coated balloon
( Wiley , 2020 , Article)Objectives: The aim of this study is to improve local-drug delivery efficiency and tissue absorption using the ultrasound (US)-responsible drug coating based on a newly developed US-controlled paclitaxel release balloon. ... -
Ultrasound diagnosis of infections in pregnancy
( Elsevier , 2021 , Article)Pregnancy is a unique period in which several changes occur in the mother, to ensure that the semiallograft fetus is not rejected. Some of these changes decrease the immunity of the mother to infections. As such, some ... -
Ultrasound Intima-Media Complex (IMC) Segmentation Using Deep Learning Models
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Common carotid intima-media thickness (CIMT) is a common measure of atherosclerosis, often assessed through carotid ultrasound images. However, the use of deep learning methods for medical image analysis, segmentation and ... -
Ultrasound-Based Image Analysis for Predicting Carotid Artery Stenosis Risk: A Comprehensive Review of the Problem, Techniques, Datasets, and Future Directions
( MDPI , 2023 , Article Review)The carotid artery is a major blood vessel that supplies blood to the brain. Plaque buildup in the arteries can lead to cardiovascular diseases such as atherosclerosis, stroke, ruptured arteries, and even death. Both ... -
Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling
( Dove Medical Press , 2020 , Article)© 2020 Alotaibi et al. Introduction: Lead (Pb) is an environmental toxic metal that threatens human health. Umbelliferone (UMB) is a coumarin with known medicinal and protective properties against cytotoxicity. This study ... -
Umbilical cord hernia associated with complete evagination of the patent omphalomesenteric duct and prolapse of adjacent ileal limbs
( Elsevier , 2021 , Other)[No abstract available] -
Undergraduate nursing and medical students' perceptions of food security and access to healthy food in Qatar: a photovoice study
( Cambridge University Press , 2022 , Article)The present study explored nursing and medical students' perceptions of food security, their access to healthy food and the circumstances that affect their access to healthy food in Qatar. The photovoice method was adopted ... -
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
( Springer Healthcare , 2019 , Article Review)Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ... -
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
( Elsevier , 2023 , Article)In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type 2 diabetes ... -
Unexpected adrenal pheochromocytoma associated with a generalized tonic-clonic seizure in a prepubertal boy: A case report.
( Lippincott, Williams & Wilkins , 2021 , Article)Pheochromocytoma (PHEO) is a rare neuroendocrine tumor arising from chromaffin cells of the adrenal medulla. Most pediatric PHEOs are functional tumors, and clinical manifestations are related to catecholamine hypersecretion ... -
Unexpected presentation of ischemic colitis: a case report and review of the literature.
( Oxford University Press , 2023 , Other)Ischemic colitis accounts for many cases of bowel infarction. Usually, it has various manifestations, such as vomiting, abdominal pain, hematochezia and many other symptoms. Risk factors might include age, medications, ... -
A unified framework for bias assessment in clinical research
( Lippincott, Williams & Wilkins , 2019 , Article)Methodological flaws, limitations, and inadequate practices in research are well known and pose threats to the internal validity of any research study. However, there are ways of safeguarding research conduct to reduce the ... -
Unifying the diagnosis of gestational diabetes mellitus: Introducing the NPRP criteria
( Elsevier , 2021 , Article)AimsDisagreement about the appropriate criteria for the diagnosis of gestational diabetes mellitus (GDM) persists. This study examines an alternative approach which combines information from all time-points on the glucose ... -
An unusual case of modified Lemierre’s syndrome caused by staphylococcus aureus cellulitis
( International Scientific Literature Inc. , 2020 , Article)Patient: Male, 31-year-old Final Diagnosis: Lemierre’s Disease Symptoms: Conjunctival injection • eye pain and redness • fever • nasal swelling • periorbital oedema • ptosis • vesicular lesions nose Medication: — Clinical ... -
Unveiling a Biomarker Signature of Meningioma: the Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
( preprints , 2023 , Preprint)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation in grades classified from I to III. Meningiomas tremendous variability in tumor behavior and slow ...