Browsing College of Medicine by Title
Now showing items 474-493 of 1375
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Elaeagnus Angustifolia Plant Extract inhibits Epithelial- mesenchymal Transition in Human Colorectal Cancer via β-catenin/JNK signaling Pathways
( University of Jordan,Deanship of Scientific Research , 2023 , Article)Elaeagnus angustifolia (EA) is a traditional plant that has been used as an alternative medicine for centuries. EA roles as anti-cancer has been investigated against different types of cancer, however, its effect against ... -
Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells
( MDPI , 2020 , Article)Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle East. Meanwhile, the outcome of extract on HER2-positive breast cancer remains nascent. Thus, we herein investigated ... -
Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications.
( Springer Verlag , 2018 , Article)Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the ... -
Elucidating the chemical profile and biological studies of Verbascum diversifolium Hochst. extracts
( Frontiers Media SA , 2024 , Article)The present study was designed to evaluate the chemical composition, antioxidant, enzyme inhibition and cytotoxic properties of different extracts from aerial parts of V. diversifolium (family Scrophulariaceae), a plant ... -
Emergency department presentations of alcohol and other substance misuse: First cross-sectional national study in Qatar
( BMJ Publishing Group , 2021 , Article)Objectives This study attempts the first in a series of investigations into the misuse of alcohol and substances in Qatar. This study explores the emergency presentations of alcohol and substance abuse to all the state ... -
EMERGENCY MEDICINE FELLOWSHIP: LENGTH-OF-STAY IMPACT OF ESTABLISHING A LARGE POST-RESIDENCY TRAINING PROGRAM
( National library of medicine , 2020 , Article)Background: The length of stay (LOS) is an important operational parameter closely followed in emergency department (ED). This study aims to assess operations impacts of a large post-residency EM Fellowship (EMF) program ... -
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)The abnormal accumulation of methylglyoxal (MG) leading to increased glycation of protein and DNA has emerged as an important metabolic stress, dicarbonyl stress, linked to aging, and disease. Increased MG glycation produces ... -
Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
( Elsevier , 2021 , Article)Drug delivery systems or vectors are usually needed to improve the bioavailability and effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an organ, tissue or cellular level. However, emerging ... -
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review.
( Oxford University Press , 2023 , Article Review)Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ... -
Emotional and Clinical Challenges While Dealing With a Blind-Deaf-Mute Patient.
( Springer , 2020 , Article)A 43-year-old male, known to be deaf, mute, and blind, presented to the ED accompanied by his daughter. She said that he had multiple episodes of diarrhea and vomiting for two days. At first, it gave the impression of ... -
Empirical Comparisons of 12 Meta-analysis Methods for Synthesizing Proportions of Binary Outcomes
( Springer , 2021 , Article)Background: Meta-analysis is increasingly used to synthesize proportions (e.g., disease prevalence). It can be implemented with widely used two-step methods or one-step methods, such as generalized linear mixed models ... -
EMT Factors and Metabolic Pathways in Cancer.
( Frontiers Media , 2020 , Article)The epithelial-mesenchymal transition (EMT) represents a biological program during which epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is normally observed during organismal development, ... -
Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs
( American Chemical Society , 2019 , Article)G-protein-coupled receptors (GPCRs) can bias signaling through distinct biochemical pathways that originate from G-protein/receptor and β-arrestin/receptor complexes. Receptor conformations supporting β-arrestin engagement ... -
Encysted hydrocele of the canal of Nuck in an 11-month-old child with a past history of duodenal atresia and Arnold-Chiari malformation: A case report.
( Wolters Kluwer Health , 2019 , Other)Hydrocele of the canal of Nuck is a rare developmental disorder and represents of a homolog of hydrocele of spermatic cord in males. Hydrocele of the canal of Nuck is a very rare cause of inguinal swelling in female infants ... -
Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes.
( MDPI , 2019 , Article)Physical inactivity and sedentary lifestyle contribute to the widespread epidemic of obesity among both adults and children leading to rising cases of diabetes. Cardiovascular disease complications associated with obesity ... -
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
( Elsevier , 2022 , Article)On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ... -
Epac as a tractable therapeutic target
( Elsevier , 2023 , Article)In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein kinase A (PKA) pathway. Since then, cAMP has received increasing ... -
The epidemic volatility index, a novel early warning tool for identifying new waves in an epidemic
( Nature Research , 2021 , Article)Early warning tools are crucial for the timely application of intervention strategies and the mitigation of the adverse health, social and economic effects associated with outbreaks of epidemic potential such as COVID-19. ... -
Epidemiologic and clinical characteristics of selected congenital anomalies at the largest Bosnian pediatric surgery tertiary center
( Lippincott, Williams & Wilkins , 2022 , Article)Congenital anomalies (CA) are any abnormality present at birth, either structural or functional, that may potentially affect an infant's health, development, and/or survival. There is a paucity of studies on clinical ... -
Epidemiology and early bacterial colonization of minor and moderate pediatric burns: A retrospective study from a developing country
( Elsevier , 2023 , Article)ObjectivesInfection is still the leading cause of morbidity and mortality among burn patients worldwide. Isolation and identification of pediatric burn wound bacterial colonizers can prevent infection and improve burn ...