Browsing College of Medicine by Title
Now showing items 1400-1419 of 1438
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Validation of a Novel Fluorescent Lateral Flow Assay for Rapid Qualitative and Quantitative Assessment of Total Anti-SARS-CoV-2 S-RBD Binding Antibody Units (BAU) from Plasma or Fingerstick Whole-Blood of COVID-19 Vaccinees
( MDPI , 2022 , Article)Background: Limited commercial LFA assays are available to provide a reliable quantitative measurement of the total binding antibody units (BAU/mL) against the receptor-binding domain of the SARS-CoV-2 spike protein (S-RBD). ... -
Validation of a risk prediction model for COVID-19: the PERIL prospective cohort study.
( Future Medicine , 2023 , Article)This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients were recruited at their initial diagnosis at two ... -
Validation of Doi's weighted average glucose as a measure of post-load glucose excursion for clinical use.
( Biomolecules and Biomedicine , 2023 , Article)In this study, we examined the performance of a novel index of glucose excursion (Doi’s weighted average glucose [dwAG]) in relation to the conventional measure of area under the oral glucose tolerance test (A-GTT) and the ... -
Validation of plasma protein glycation and oxidation biomarkers for the diagnosis of autism
( Springer Nature , 2023 , Article)Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder in children. It is currently diagnosed by behaviour-based assessments made by observation and interview. In 2018 we reported a discovery study of a ... -
Validation of the 6-Month GRACE Score in Predicting 1-Year Mortality of Patients With Acute Coronary Syndrome Admitted to the Arabian Gulf Hospitals
( SAGE Publications , 2016 , Article)Acute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge ... -
Validity of clinical disease activity index (CDAI) to evaluate the disease activity of rheumatoid arthritis patients in Sri Lanka: A prospective follow up study based on newly diagnosed patients
( Public Library of Science , 2022 , Article)Routine use of the Disease Activity Score-28 (DAS28) to assess the disease activity in rheumatoid arthritis (RA) is limited due to its dependency on laboratory investigations and the complex calculations involved. In ... -
Value of additional sections: Tissue handling of small biopsies in detecting squamous dysplasia of the uterine cervix
( Elsevier , 2022 , Article)Cervical cancer screening is currently based on high-risk human papillomavirus (HR-HPV) molecular testing, Pap cytology testing, and histologic evaluation of cervical biopsies. As primary HPV screening for cervical cancer ... -
The vascular glycocalyx is not a mechanosensor in conduit arteries in the anesthetized pig.
( PeerJ , 2020 , Article)The role of the glycocalyx as the endothelial sensor of an increase in blood flow was assessed in the iliac artery in vivo. Acetylcholine-induced flow mediated dilation was evaluated before and after vascular glycocalyx ... -
Vascular inflammation: Players and modulators
( Bentham Science Publishers , 2021 , Other)- -
Vasoactive pharmacologic therapy in cardiogenic shock: a critical review.
( Taylor & Francis , 2021 , Article)Cardiogenic shock (CS) is an acute complex condition leading to morbidity and mortality. Vasoactive medications, such as vasopressors and inotropes are considered the cornerstone of pharmacological treatment of CS to improve ... -
Venous Thromboembolism Among Hospitalized Patients: Incidence and Adequacy of Thromboprophylaxis – A Retrospective Study
( Taylor & Francis Group , 2022 , Article)Purpose: We aimed to determine the incidence of venous thromboembolism among hospitalized patients in Qatar as well as to analyze the adequacy of VTE assessment and prophylaxis in hospitalized patients. Design: Retrospective ... -
Ventilator-associated pneumonia diagnosis: electrochemical sensors for rapid and sensitive detection of pyocyanin
( Springer Nature , 2024 , Article)Ventilator-associated pneumonia (VAP) is a severe condition in critically ill patients that requires timely diagnosis to improve patient outcomes. In this study, we developed an electrochemical sensor for pyocyanin detection ... -
Virtual Reality Module Depicting Catheter-Associated Urinary Tract Infection as Educational Tool to Reduce Antibiotic Resistant Hospital-Acquired Bacterial Infections
( Institute of Electrical and Electronics Engineers Inc. , 2020 , Conference Paper)Virtual Reality (VR) and augmented reality (AR) are used as simulation models in student-patient interactive medical education and shown to enhance learning outcomes. The rise in global burden of infectious diseases ... -
Visfatin : An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases
( Wiley , 2021 , Article)Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been implicated in vascular remodeling, vascular ... -
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ... -
Vitamin D and Its Potential Interplay With Pain Signaling Pathways
( Frontiers Media , 2020 , Article Review)About 50 million of the U.S. adult population suffer from chronic pain. It is a complex disease in its own right for which currently available analgesics have been deemed woefully inadequate since ~20% of the sufferers ... -
Vitamin D for the Immune System in Cystic Fibrosis (DISC): A double-blind, multicenter, randomized, placebo-controlled clinical trial
( Oxford University Press , 2019 , Article)Background Patients with cystic fibrosis (CF) have increased risk of vitamin D deficiency owing to fat malabsorption and other factors. Vitamin D deficiency has been associated with increased risk of pulmonary exacerbations ... -
Vitamin D status affects proteomic profile of HDL-associated proteins and inflammatory mediators in dyslipidemia
( Elsevier , 2024 , Article)Vitamin D deficiency and dyslipidemia have substantial implications for human health globally. Vitamin D is essential for bone metabolism and immune modulation, and its insufficiency is linked to various chronic inflammatory ... -
Voltage dependence of the Ca2+ transient in endocardial and epicardial myocytes from the left ventricle of Goto Kakizaki type 2 diabetic rats
( Springer New York LLC , 2018 , Article)Diabetes mellitus is a major global health disorder and, currently, over 450 million people have diabetes with 90% suffering from type 2 diabetes. Left untreated, diabetes may lead to cardiovascular diseases which are a ... -
Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity—Opportunity for Repurposed Chemotherapy of COVID-19 Infection
( Frontiers Media , 2020 , Article)The global pandemic of COVID-19 disease caused by infection with the SARS-CoV-2 coronavirus, has produced an urgent requirement and search for improved treatments while effective vaccines are developed. A strategy for ...