Browsing College of Medicine by Subject "Genome-wide association studies"

Now showing items 1-2 of 2

    • Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants 

      Aragam, Krishna G.; Jiang, Tao; Goel, Anuj; Kanoni, Stavroula; Wolford, Brooke N.; ... more authors ( Nature Research , 2022 , Article)
      The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) ...

    • The power of genetic diversity in genome-wide association studies of lipids 

      Graham, Sarah E.; Clarke, Shoa L.; Wu, Kuan Han H.; Kanoni, Stavroula; Zajac, Greg J.M.; ... more authors ( Nature Research , 2021 , Article)
      Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use1. Despite advances in prevention and treatment, in ...