Browsing College of Medicine by Title
Now showing items 151-170 of 1328
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Bias assessment: mQ or RoB?
( Lippincott, Williams & Wilkins , 2023 , Other)In a recent paper in the journal, Stone et al. propose that JBI adopt the term risk of bias (RoB) wherever critical appraisal, study validity, method- ological quality (mQ), or methodological limitations are used. The ... -
Biased agonism at G protein-coupled receptors
( Elsevier , 2021 , Other)G protein-coupled receptors (GPCRs) represent the largest family of approved therapeutic targets. Ligands stimulating these receptors specifically activate multiple signalling pathways that induce not only the desired ... -
Biased signaling: A viable strategy to drug ghrelin receptors for the treatment of obesity
( Elsevier , 2021 , Article)Obesity is a global burden and a chronic ailment with damaging overall health effects. Ghrelin, an octanoylated 28 amino acid peptide hormone, is secreted from the oxyntic mucosa of the stomach. Ghrelin acts on regions of ... -
A Bibliometric Analysis and Visualization of Decision Support Systems for Healthcare Referral Strategies
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: The referral process is an important research focus because of the potential consequences of delays, especially for patients with serious medical conditions that need immediate care, such as those with metastatic ... -
Bibliometric analysis of adverse drug reactions and pharmacovigilance research activities in Nepal
( Sage , 2020 , Article)Background: Bibliometric analyses have been used previously to study the measures of quality and impact of research performed in several health-related areas such as adverse drug reactions (ADRs) and pharmacovigilance (PV), ... -
Bilateral adnexal masses: A case report of acute myeloid leukemia presenting with myeloid sarcoma of the ovary and review of literature
( Elsevier , 2023 , Article)Here, we report a case of myeloid sarcoma (extramedullary myeloid tumor) of the left ovary in a female with known acute myeloid leukemia (AML), who was discovered to have bilateral adnexal masses during treatment planning ... -
Bilateral Morgagni hernia in a two-month-old infant with a history of umbilical cord hernia status-post repair in neonatal period
( Elsevier , 2022 , Other)Morgagni hernias (MH) are a rare form of congenital diaphragmatic hernia (CDH) characterized by herniation of abdominal contents into the thoracic cavity through a retrosternal diaphragmatic defect. MH constitutes <5% of ... -
BIO-CXRNET: a robust multimodal stacking machine learning technique for mortality risk prediction of COVID-19 patients using chest X-ray images and clinical data
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Nowadays, quick, and accurate diagnosis of COVID-19 is a pressing need. This study presents a multimodal system to meet this need. The presented system employs a machine learning module that learns the required knowledge ... -
Biochemical and cellular basis of oxidative stress: Implications for disease onset
( Wiley , 2023 , Article Review)Cellular oxidation–reduction (redox) systems, which encompass pro- and antioxidant molecules, are integral components of a plethora of essential cellular processes. Any dysregulation of these systems can cause molecular ... -
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
( Portland Press Ltd , 2024 , Article)Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 50-phosphate (PLP)-dependent enzyme in the transsulfuration ... -
Biological applications of imiquimod analogues: An update (Review)
( Spandidos Publications , 2023 , Article Review)The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ... -
A Biomarker Based Severity Progression Indicator for COVID-19: The Kuwait Prognosis Indicator Score.
( Taylor and Francis , 2020 , Article)COVID-19 is a worldwide pandemic that is mild in most patients but can result in a pneumonia like illness with progression to acute respiratory distress syndrome and death. Predicting the disease severity at time of diagnosis ... -
Biomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast.
( Lippincott, Williams & Wilkins , 2019 , Article)The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases to the ... -
Biomaterials in Traumatic Brain Injury: Perspectives and Challenges
( MDPI , 2023 , Article Review)Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ... -
Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis
( Public Library of Science , 2020 , Article)The association between blood pressure (BP) and bladder cancer (BC) risk remains unclear with confounding by smoking being of particular concern. We investigated the association between BP and BC risk among men using ... -
Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Autism spectrum disorder (ASD) is an umbrella term that encompasses several disabling neurodevelopmental conditions. These conditions are characterized by impaired manifestation in social and communication skills with ... -
Book review: food and brain health
( Wolters Kluwer , 2023 , Book Review)In 2014, a book entitled “Food and Brain Health” was published by a reputable US-based publisher Nova Science Publishers, Inc, New York. The book is authored and edited by a group of scientists, Dr Musthafa Mohamed Essa ... -
Bosnian Journal of Basic Medical Sciences becomes Biomolecules and Biomedicine
( National Library of Medicine , 2023 , Other)The Bosnian Journal of Basic Medical Sciences (BJBMS) was founded in 1998 in Sarajevo, Bosnia and Herzegovina, by Professor Muzafer Mujić, Professor of Physiology at the Faculty of Medicine, University of Sarajevo. Most ... -
Bowel Dilatation on Initial Plane Abdominal Radiography May Help to Assess the Severity of Necrotizing Enterocolitis in Preterm Infants.
( MDPI , 2020 , Article)Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency associated with prematurity. Timely diagnosis and adequate treatment are crucial to reduce the morbidity and mortality of the ... -
BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)The BRCA1 is a tumor suppressor gene that encodes for the BRCA1 protein, which plays a vital role in DNA repair, cell cycle regulation, and the maintenance of genomic stability. The BRCA1 protein interacts with a variety ...