Browsing College of Medicine by Title
Now showing items 770-789 of 1418
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KIR genotype and haplotype repertoire in Kuwaiti healthy donors, hematopoietic cell transplant recipients and healthy family members
( John Wiley and Sons Inc , 2023 , Article)The gene complex located on chromosome 19q13.4 encodes the Killer-cell Immunoglobulin-like Receptors (KIRs), which exhibit remarkable polymorphism in both gene content and sequences. Further, the repertoire of KIR genes ... -
Knowledge, attitude and practices related to COVID-19 among young Lebanese population
( BioMed Central Ltd , 2021 , Article)Background: As the world faces the most serious and widespread pandemic in recent history, claiming nearly 1,945,610 lives and infecting over 90 million individuals up to January 13, 2021, controlling the spread of COVID-19 ... -
Knowledge, Attitude, Practices, and Sources of Information (KAPS) toward COVID-19 during the second wave pandemic among university population in Qatar: A cross-sectional study
( Frontiers Media , 2022 , Article)Background: The World Health Organization (WHO) declared COVID-19 as a pandemic on 11 March 2020. Many efforts were performed to contain the virus worldwide. People's knowledge and attitude should be directed toward strict ... -
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
( Nature Research , 2021 , Article)Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs. Cells express thousands of mostly mobile ... -
Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy
( Dove Press Ltd , 2024 , Article)Background & Objective: Chronic peripheral neuropathic pain (PNP) is a debilitating condition that is associated with many types of injury/diseases, including diabetes mellitus. Patients with longstanding diabetes develop ... -
KYNU, a novel potential target that underpins CD44-promoted breast tumour cell invasion
( Blackwell Publishing Inc. , 2021 , Article Review)Using a validated tetracycline-off-inducible CD44 expression system in mouse model, we have previously demonstrated that the hyaluronan (HA) receptor CD44 promotes breast cancer (BC) metastasis to the liver. To unravel the ... -
L5 Spinal Nerve Axotomy Induces Distinct Electrophysiological Changes in Axotomized L5- and Adjacent L4-Dorsal Root Ganglion Neurons in Rats .
( Mary Ann Liebert , 2020 , Article)Peripheral neuropathic pain (PNP) is a major health problem for which effective drug treatment is lacking. Its underlying neuronal mechanisms are still illusive, but pre-clinical studies using animal models of PNP including ... -
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic.
( BMC , 2020 , Article)Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ... -
Laparoscopic Extirpation of Adrenal Gland Ganglioneuroma Incidentally Diagnosed During Evaluation for Patchy Alopecia Areata in an Adolescent Boy
( Karger , 2019 , Article)We present a 17-year-old boy with an incidentally diagnosed left adrenal ganglioneuroma (GN) during the diagnostic work up of alopecia areata (AA). Clinical Presentation and Intervention Laboratory investigations revealed ... -
Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
( BMC , 2020 , Article)© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ... -
Large expanding splenic pseudocyst: A case report and review of literature
( Elsevier , 2021 , Article)Introduction and importance Splenic pseudocysts are extremely uncommon. Most of these cysts are asymptomatic and may result from previous blunt abdominal trauma. We report an interesting uncommon case of large splenic ... -
Large uterine juvenile cystic adenomyoma in an adolescent
( Elsevier , 2022 , Article)Juvenile cystic adenomyoma (JCA) is a rare uterine pathology with <40 cases reported in the current literature since 1996 when Tamura described it. We report a 13-year-old girl with a history of chronic pelvic pain and ... -
A large, highly vascularized sacrococcygeal teratoma in a preterm male infant: A case report.
( Elsevier , 2021 , Article)Sacrococcygeal teratoma (SCT) is a rare tumor with an incidence of 1:35.000/40.000 live births. SCTs are composed of both cystic and solid components. Predominantly cystic SCTs are more likely to be benign and have a better ... -
Late-diagnosed complete intravaginal testicular torsion with preserved blood flow and viable testis in an adolescent
( Elsevier , 2023 , Other)To the Editor, Testicular torsion (TT) is an emergency caused by the twisting of the spermatic cord. In addition to being complete, TT can be partial or intermittent. The degree of spermatic cord twist in partial or ... -
Lecturing skills as predictors of tutoring skills in a problem-based medical curriculum
( Dove Press , 2016 , Article)Purpose: Recruitment of tutors to work in problem-based learning (PBL) programs is challenging, especially in that most of them are graduated from discipline-based programs. Therefore, this study aims at examining whether ... -
Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight-loss interventions
( John Wiley and Sons Inc , 2024 , Article Review)Childhood obesity represents a significant public health concern, imposing a substantial burden on the healthcare system. Furthermore, weight-loss programs often exhibit reduced effectiveness in adults who have a history ... -
Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats
( Elsevier , 2023 , Article)Background: The timely abortion of status epilepticus (SE) is essential to avoid brain damage and long-term neurodevelopmental sequalae. However, available anti-seizure treatments fail to abort SE in 30% of children. Given ... -
Letter re: stratification by quality is not recommended in meta-analysis.
( Elsevier , 2019 , Other)None -
Letter to editor/comment
( Blackwell Publishing Inc. , 2019 , Other)[No abstract available] -
Letter to editor/comment : Metaplastic carcinoma of the breast: Prognosis and response to systemic treatment in metastatic disease
( Wiley , 2019 , Other)Comment on the recent paper on metaplastic breast carcinoma study published in the Breast Journal 2019.