Browsing College of Medicine by Publisher "Elsevier B.V."
Now showing items 1-7 of 7
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Diagnostic value of bronchoalveolar lavage in the subset of patients with negative sputum/smear and mycobacterial culture and a suspicion of pulmonary tuberculosis
( Elsevier B.V. , 2019 , Article)Background: The diagnostic value of bronchoalveolar lavage in patients with negative sputum/smear for tuberculous bacilli has been well studied. However, its value in the subset of patients with both negative sputum/smear ... -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
Group OSCE (GOSCE) as a formative clinical assessment tool for pre-clerkship medical students at the University of Sharjah
( Elsevier B.V. , 2018 , Article)Objectives: Continuous formative assessment with appropriate feedback is the pillar of effective clinical teaching and learning. Group Objective Structured Clinical Examination (GOSCE) has been reported as a resource-effective ... -
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
( Elsevier B.V. , 2024 , Article)The unfolded protein response (UPR) detects increased misfolded proteins and activates protein refolding, protein degradation and inflammatory responses. UPR sensors in the endoplasmic reticulum, IRE1α and PERK, bind and ... -
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
( Elsevier B.V. , 2017 , Article)The critical role of α1-glycine receptor (α1-GLYRs) in pathological conditions such as epilepsy is well known. In the present study, structure-activity relations for a series of phenylalanine derivatives carrying selected ... -
Targeted delivery of rifampicin to tuberculosis-infected macrophages: design, in-vitro, and in-vivo performance of rifampicin-loaded poly(ester amide)s nanocarriers
( Elsevier B.V. , 2016 , Article)We have developed a nano drug delivery system for the treatment of tuberculosis (TB) using rifampicin (RF) encapsulated in poly(ester amide)s nanoparticles (PEA-RF-NPs), which are biocompatible polymers. In this study, ... -
What is open-access publishing and what it means for the forensic enterprise
( Elsevier B.V. , 2019 , Article)Science is a public endeavor the results of which are intended to be shared with other scientists, professionals, and the public [1]. This is viewed as a worldwide right: Article 27 of the United Nations Declaration of ...