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The characteristics and prognostic significance of histone H1 expression in breast cancer
(
Elsevier
, 2024 , Article)
Histone H1 (H.H1) is involved in chromatin organisation and gene regulation and is overexpressed in many malignant tumours, including breast cancer (BC). This study proposed and evaluated the prognostic role of H.H1 ...
Cranial measurements obtained by three-dimensional computed tomography technique in the estimation of sex of contemporary Black South Africans
(
Elsevier
, 2024 , Article)
Human identification forms an integral part of forensic and biological anthropology. For proper identification, a biological profile made up of biodata such as age, sex, ancestry, antemortem stature, and factors of ...
A novel deep learning technique for morphology preserved fetal ECG extraction from mother ECG using 1D-CycleGAN
(
Elsevier
, 2024 , Article)
The non-invasive fetal electrocardiogram (fECG) enables easy detection of developing heart abnormalities, leading to a significant reduction in infant mortality rate and post-natal complications. Due to the overlapping of ...
Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis
(2024 , Article)
CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review ...
An investigation of endometrial vascularity in normally menstruating women and those in other physiological states using 3D ultrasound imaging
(
Wiley-Blackwell
, 2024 , Article)
Objectives: This study aimed to determine the normal vasculature indices of the endometrium and to correlate them with those in various physiological states. Methods: Women undergoing ultrasound at the Feto-Maternal Center, ...
C-peptide in diabetes: A player in a dual hormone disorder?
(
Wiley-Blackwell
, 2024 , Article)
C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ...
Seroprevalence of small ruminant brucellosis in the state of Qatar
(
Wiley-Blackwell
, 2024 , Article)
Background: Brucellosis is one of the most important zoonotic diseases worldwide, with a significant economic and health burden. The disease is endemic in many regions around the world. Data regarding the disease in the ...
Phenotypic switching of vascular smooth muscle cells in atherosclerosis, hypertension, and aortic dissection
(
Wiley-Blackwell
, 2024 , Article)
Vascular smooth muscle cells (VSMCs) play a critical role in regulating vasotone, and their phenotypic plasticity is a key contributor to the pathogenesis of various vascular diseases. Two main VSMC phenotypes have been ...
Thromboxane biosynthesis and future events in diabetes: the ASCEND trial
(
Oxford University Press
, 2024 , Article)
Background and Thromboxane (TX) A2, released by activated platelets, plays an important role in atherothrombosis. Urinary 11-dehydro-Aims TXB2 (U-TXM), a stable metabolite reflecting the whole-body TXA2 biosynthesis, is ...
CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs
(
Frontiers Media SA
, 2024 , Article)
Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM ...