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Mutagenesis-Based Characterization and Improvement of a Novel Inclusion Body Tag
(
Frontiers Media
, 2020 , Article)
Whereas, bacterial inclusion bodies (IBs) for long were regarded as undesirable aggregates emerging during recombinant protein production, they currently receive attention as promising nanoparticulate biomaterials with ...
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic.
(
BMC
, 2020 , Article)
Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ...
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
(
Nature Publishing Group
, 2020 , Article)
Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. We reported levels of serum protein glycation, oxidation and nitration and related hydrolysis products, glycation, ...
Physical activity in pregnancy prevents gestational diabetes: A meta-analysis
(
Elsevier
, 2020 , Article)
AimsThe effectiveness of physical activity (PA) programs for prevention of gestational diabetes (GDM) lacks conclusive evidence. The aim of this study was to generate clear evidence regarding the effectiveness of physical ...
Decreased number of acute appendicitis cases in pediatric population during the COVID-19 pandemic: Any link?
(
Elsevier
, 2020 , Article)
The reasons behind the decrease in AA frequency during the COVID-19 pandemic remain unclear. Some authors have proposed that milder forms can be treated conservatively at home [15] or using antibiotics. Snapiri et al. also ...
The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
(
MDPI
, 2020 , Article)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Autophagy is a homeostatic process that regulates and recycles intracellular structures and is a host defense mechanism that facilitates bacterial clearance. Uric ...
Meningococcal Vaccines: Challenges and Prospects.
(
MDPI
, 2020 , Article)
is a gram-negative bacterium that causes a severe acute infection, called the meningococcal disease [...].
Urine as a Main Effector in Urological Tissue Engineering—A Double-Edged Sword
(2020 , Article)
In order to reconstruct injured urinary tract tissues, biodegradable scaffolds with autologous seeded cells are explored in this work. However, when cells are obtained via biopsy from individuals who have damaged organs ...
High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human Cervical Cancer: Recent Evidence and Future Directions
(
Frontiers Media
, 2020 , Article)
Cervical cancer is the fourth most common malignancy in women worldwide and a leading cause of cancer-related mortality in developing countries. Important etiological factors in this cancer are high-risk human papillomaviruses ...
"Practice Educators' Academy": A fundamental step to experiential training success in Qatar
(
Hamad bin Khalifa University Press (HBKU Press)
, 2020 , Article)
Background: Experiential learning is the backbone of many healthcare professional education programs 1 , and the quality of experiential learning is dependent on the skills, experiences, and proficiency of the clinical ...