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Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?
(
Company of Biologists Ltd
, 2018 , Article)
The cardiac muscle ryanodine receptor-Ca2+ release channel (RyR2) constitutes the sarcoplasmic reticulum (SR) Ca2+ efflux mechanism that initiates myocyte contraction, while cardiac myosin-binding protein-C (cMyBP-C; also ...
Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers.
(
Public Library of Science
, 2020 , Article)
Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors used for cellular reprogramming, a role ...
The Non-Coding RNA and Its Role in Tumor Therapy-Induced Resistance.
(
MDPI
, 2020 , Article)
The growth arrest-specific transcript 5 () is a >200-nt lncRNA molecule that regulates several cellular functions, including proliferation, apoptosis, invasion and metastasis, across different types of human cancers. Here, ...
The MethodologicAl STandards for Epidemiological Research (MASTER) scale demonstrated a unified framework for bias assessment
(
Elsevier
, 2021 , Article)
Objective: This paper presents a unified framework for assessment of the methodological quality of analytic study designs. Study Design and Setting: A systematic review of 393 methodological quality assessment tools that ...
Endoplasmic Reticulum Stress: A Critical Molecular Driver of Endothelial Dysfunction and Cardiovascular Disturbances Associated with Diabetes.
(
MDPI
, 2019 , Article)
Physical inactivity and sedentary lifestyle contribute to the widespread epidemic of obesity among both adults and children leading to rising cases of diabetes. Cardiovascular disease complications associated with obesity ...
68 Ga-PSMA PET/CT tumour intensity pre-operatively predicts adverse pathological outcomes and progression-free survival in localised prostate cancer
(
Springer
, 2020 , Article)
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: Prostate-specific membrane antigen (PSMA) positron emission tomography (PSMA-PET) improves prostate cancer staging. Intraprostatic PSMA intensity may ...
Global incidence of caesarean deliveries on maternal request: a systematic review and meta-regression.
(
Wiley
, 2020 , Article)
Caesarean delivery on maternal request (CDMR) is considered a significant contributor to the unprecedented increase in caesarean deliveries (CDs) for nonclinical reasons. Current literature lacks a reliable assessment of ...
Measuring medical students' professional competencies in a problem-based curriculum: A reliability study
(
BioMed Central Ltd.
, 2019 , Article)
Identification and assessment of professional competencies for medical students is challenging. We have recently developed an instrument for assessing the essential professional competencies for medical students in ...
Seasonality and community interventions in a mathematical model of Clostridium difficile transmission
(
W.B. Saunders Ltd
, 2019 , Article)
Background: Clostridium difficile infection (CDI)is the leading cause of antibiotic-associated diarrhoea with peak incidence in late winter or early autumn. Although CDI is commonly associated with hospitals, community ...
Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis
(
Public Library of Science
, 2020 , Article)
The association between blood pressure (BP) and bladder cancer (BC) risk remains unclear with confounding by smoking being of particular concern. We investigated the association between BP and BC risk among men using ...