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Racing for COVID-19 Vaccine and Cure: Lessons and Tragedies in Human Subject Research.
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Medknow Publications
, 2020 , Article)
Pressured by the enormous human and economic costs of the COVID-19 pandemic, certain countries and political figures have advocated the use of drugs and vaccines that did not go through the required regulatory stages of ...
The attitude and knowledge of pediatricians and family physicians toward COVID-19 vaccination in children: A cross-sectional study
(
Taylor and Francis Ltd.
, 2023 , Article)
COVID-19 vaccines to children are expected to reduce the transmission of the disease to high-risk groups and achieve herd immunity in younger populations. A positive attitude toward COVID-19 vaccination in children among ...
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
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Bentham Science Publishers
, 2020 , Article)
Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ...
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis.
(
Taylor & Francis
, 2022 , Article)
This study aims to estimate the prevalence and longevity of detectable SARS-CoV-2 antibodies and T and B memory cells after recovery. In addition, the prevalence of COVID-19 reinfection and the preventive efficacy of ...
Prevalence of Venous Thromboembolism in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis
(
Frontiers Media S.A.
, 2021 , Article)
Background: Recent studies revealed a high prevalence of venous thromboembolism (VTE) events in coronavirus disease 2019 (COVID-19) patients, especially in those who are critically ill. Available studies report varying ...
Validation of a Novel Fluorescent Lateral Flow Assay for Rapid Qualitative and Quantitative Assessment of Total Anti-SARS-CoV-2 S-RBD Binding Antibody Units (BAU) from Plasma or Fingerstick Whole-Blood of COVID-19 Vaccinees
(
MDPI
, 2022 , Article)
Background: Limited commercial LFA assays are available to provide a reliable quantitative measurement of the total binding antibody units (BAU/mL) against the receptor-binding domain of the SARS-CoV-2 spike protein (S-RBD). ...
Duration of COVID-19 mRNA Vaccine Effectiveness against Severe Disease
(
MDPI
, 2022 , Article)
Waning immunity following administration of mRNA-based COVID-19 vaccines remains a concern for many health systems. We undertook a study to determine if recent reports of waning for severe disease could have been attributed ...
Structures, processes and outcomes of objective structured clinical examinations in dental education during the COVID-19 pandemic: A scoping review
(
Wiley-Blackwell
, 2022 , Article)
Introduction: Objective structured clinical examinations (OSCEs) are an essential examination tool within undergraduate dental education. Fear of spread of the COVID-19 virus led to dental institutions exploring alternative ...
Efficacy of chloroquine and hydroxychloroquine in treating COVID-19 infection: A meta-review of systematic reviews and an updated meta-analysis
(
Elsevier
, 2021 , Article)
To synthesize findings from systematic reviews and meta-analyses on the efficacy and safety of chloroquine (CQ) and hydroxychloroquine (HCQ) with or without Azithromycin for treating COVID-19, and to update the evidence ...
In sickness and in health: The politics of public health and their implications during the COVID-19 pandemic
(
Wiley
, 2021 , Article)
Politics is a major player in health, sickness, and death affairs. This article reviews the role of politics in public health and its impact on health outcomes, mortality ratios, and death scenarios amongst the most ...