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Can atorvastatin with metformin change the natural history of prostate cancer as characterized by molecular, metabolomic, imaging and pathological variables? A randomized controlled trial protocol
(
Elsevier
, 2016 , Article)
Background Atorvastatin and metformin are known energy restricting mimetic agents that act synergistically to produce molecular and metabolic changes in advanced prostate cancer (PCa). This trial seeks to determine whether ...
Prostate biopsy, targeted prophylaxis and infectious complications: a critique of methods used
(
Wiley
, 2016 , Article)
Commentary
Exploring Gender Difference in Sleep Quality of Young Adults: Findings from a Large Population Study
(
Marshfield Clinic Research Foundation
, 2016 , Article)
To explore if gender difference in sleep quality is due to higher prevalence of depression in females, and whether socio-demographic and lifestyle factors have a differential effect on sleep quality in males and females. ...
Identification of a 48 kDa form of unconventional myosin 1c in blood serum of patients with autoimmune diseases.
(
Elsevier
, 2016 , Article)
We searched for protein markers present in blood serum of multiple sclerosis (MS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients in comparison to healthy human individuals. We used precipitati ...
Sleep quality and obesity in young subjects: a meta-analysis
(
Wiley
, 2016 , Article)
To assess the effect of poor sleep quality on Overweight/Obesity (Ow/Ob) in young subjects, and explore if this association is independent of sleep duration. Pubmed, EMBASE, and MEDLINE databases were searched for papers ...
The McGill Brisbane Symptom Score in relation to survival in pancreatic adenocarcinoma: a validation study
(
Springer
, 2016 , Article)
The McGill Brisbane Symptom Score (MBSS) is a clinical score for pancreatic cancer patients upon initial presentation that takes into account four variables (weight loss, abdominal pain, jaundice, and history of smoking) ...
Specific gene patterns and molecular pathways related to human carcinogenesis in different populations among various geographic locations.
(
Wiley
, 2016 , Other)
We read with great interest the article by Beg et al,1 which was recently published in Cancer. Colorectal cancers (CRCs) are the most commonly diagnosed malignancies, accounting for approximately 1.36 million new cases ...
Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function
(
Blackwell Publishing Ltd
, 2016 , Article)
Hereditary leukonychia is a rare genetic nail disorder characterized by distinctive whitening of the nail plate of all 20 nails. Hereditary leukonychia may exist as an isolated feature, or in simultaneous occurrence with ...
Validation of the 6-Month GRACE Score in Predicting 1-Year Mortality of Patients With Acute Coronary Syndrome Admitted to the Arabian Gulf Hospitals
(
SAGE Publications
, 2016 , Article)
Acute coronary syndromes (ACS) are the most common cardiovascular diseases and are associated with a significant risk of mortality and morbidity. The Global Registry of Acute Coronary Events (GRACE) risk score postdischarge ...
Effects of topiramate on pregnancy outcome in rats
(
Bahrain Medical Bulletin
, 2016 , Article)
Background: Anti-epileptics taken during pregnancy might lead to low birth-weight and birth defects which could be associated with neonatal morbidity and mortality. Objective: To evaluate the effects of maternal exposure ...