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Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety
(
Taylor and Francis Ltd
, 2020 , Article Review)
The COVID-19 pandemic is caused by the severe acute-respiratory-syndrome-coronavirus-2 that uses ACE2 as its receptor. Drugs that raise serum/tissue ACE2 levels include ACE inhibitors (ACEIs) and angiotensin-II receptor ...
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
(
Frontiers Media S.A.
, 2021 , Article)
Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. It ...
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
(
Dove Medical Press Ltd.
, 2020 , Article)
Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ...