College of Medicine: Recent submissions
Now showing items 1-20 of 1736
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Overcoming challenges in prevalence meta-analysis: the case for the Freeman-Tukey transform
( BioMed Central , 2025 , Article)Background: Traditional statistical methods assume normally distributed continuous variables, making them unsuitable for analysis of prevalence proportions. To address this problem, two commonly utilized variance-stabilizing ... -
Comparative Efficacy of Subcutaneous Versus Intravenous Interleukin 12/23 Inhibitors for the Remission of Moderate to Severe Crohn’s Disease: A Systematic Review and Meta-Analysis
( MDPI , 2025 , Article)Background/Objectives: Interleukin 12/23 inhibitors are a newer class of monoclonal antibodies used to induce and maintain remission for Crohn’s disease (CD), a chronic inflammatory bowel disease, when patients do not ... -
The Clinicopathological and Prognostic Value of CCR7 Expression in Breast Cancer Throughout the Literature: A Systematic Review and Meta-Analysis.
( MDPI , 2025 , Article)This study aimed to determine the clinicopathological findings and prognostic value of chemokine receptor 7 (CCR7) expression in patients with breast cancer (BC). Up to the 25th of March 2025, a search was conducted using ... -
From significance to divergence: guiding statistical interpretation through language
( Wolters Kluwer Health , 2025 , Article)Purpose of review P values have long been central to medical research reporting, with the term ‘‘statistical significance’’ and a P value threshold of 0.05 being in common use since 1925. Despite a century of use, P values ... -
Effects of double data extraction on errors in evidence synthesis: a crossover, multicenter, investigator-blinded, randomized controlled trial.
( Oxford University Press , 2025 , Article)The objective was to investigate the role of double extraction in reducing data errors in evidence synthesis for pharmaceutical and non-pharmaceutical interventions. Crossover randomized controlled trial (RCT). University ... -
Reply to Letter to the Editor on “Hypospadias Reconstruction Training: Development of an Ex-Vivo Model and Objective Evaluation of Surgical Skills”
( Elsevier , 2025 , Other)Thank you for the opportunity to respond to the comments regarding our article on hypospadias surgery training through a 1-day surgical course. We appreciate the detailed insights provided and would like to address each ... -
Investigating the impact of trial retractions on the healthcare evidence ecosystem (VITALITY Study I): retrospective cohort study.
( BMJ Publishing Group Ltd , 2025 , Article)To investigate the impact of retracted trials on the production and use of healthcare evidence in the evidence ecosystem. Retrospective cohort study based on forward citation searching. Retraction Watch up to 5 November ... -
Hormonal predictors of the lean phenotype in humans.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity is characterized by excessive fat accumulation and an increased risk of numerous associated comorbidities. Adipose tissue secretes leptin and other adipokines, which play key roles in regulating energy ... -
Hormonal predictors of the insulin sensitive phenotype in humans.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and a heightened risk of comorbidities. This study aimed to identify hormonal predictors of an insulin-sensitive ... -
Problematic trials are contaminating the evidence ecosystem.
( BMJ Publishing Group Ltd , 2025 , Article)As clinicians, we navigate complex decision making in our daily clinical practice. These decisions are based on our expertise, guided by clinical guidelines, and grounded in the most up-to-date evidence. An important part ... -
Effects of Trehalose Administration in Patients with Mucopolysaccharidosis Type III
( Bentham Science Publishers , 2023 , Article)Background and Aim: Mucopolysaccharidosis type III (MPS III) is a rare autosomal recessive lysosomal storage disease (LSD) caused by a deficiency of lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs), ... -
COVID-19 vaccine hesitancy and intentions among parents of children with mental and behavioral disorders
( Taylor & Francis , 2024 , Article)Parent vaccine hesitancy (PVH) remains a significant public health concern, particularly emphasized during the COVID-19 pandemic. This study investigates PVH among parents of children with various psychiatric and ... -
Genetic polymorphisms influencing antihypertensive drug responses
( John Wiley and Sons Inc , 2025 , Article Review)Hypertension is a major contributor to cardiovascular disease and its associated morbidity and mortality. The low efficacy observed with some anti-hypertensive therapies has been attributed partly to inter-individual genetic ... -
ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies
( Elsevier , 2024 , Article)Donor-specific anti-HLA antibodies (DSA) are an important cause of engraftment failure and may negatively impact survival outcomes of patients receiving allogeneic hematopoietic stem cell transplantation (HSCT) using an ... -
Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity
( Elsevier , 2024 , Article)This controlled study investigated metabolic changes in non-vaccinated individuals with Long-COVID-19, along with their connection to the severity of the disease. The study involved 88 patients who experienced varying ... -
Beyond fat: Does semaglutide affect lean mass?
( Elsevier , 2025 , Article)This opinion paper aims to discuss the influence of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), on lean mass beyond its impact on weight loss. Although significant weight loss is achieved with ... -
Corrigendum to “Impact of on-hours versus off-hours admission on outcome in pediatric patients with testicular torsion” [American Journal of Emergency Medicine 2025;88:1-6]
( Elsevier , 2025 , Article)The authors regret that the acknowledgement to Qatar National Library (QNL) for covering article processing fee was omitted from the final version of the published manuscript. The authors would like to apologise for any ... -
HPV-Related Cancers in Bosnia and Herzegovina: A Comprehensive Review
( Academy of Sciences and Arts of Bosnia and Herzegovina , 2024 , Article)This review assesses the burden of human papillomavirus (HPV)-related cancers in Bosnia and Herzegovina (BH), aiming to inform strategies for prevention and early detection. Despite the availability of highly effective HPV ... -
Association between gestational diabetes mellitus diagnostic criteria and adverse pregnancy outcomes-a systematic review and meta-analysis of adjusted effect sizes from studies using current diagnostic criteria
( BMJ Publishing Group , 2024 , Article)Objectives To quantify the association between Gestational Diabetes Mellitus (GDM) and adverse pregnancy outcomes and primarily compare the associations between diagnostic criteria following the International Association ... -
The role of interleukin 17 in cancer: a systematic review
( Oxford University Press , 2025 , Article Review)Interleukin 17 (IL17) is a cytokine involved in immune regulation and has been increasingly recognized for its role in cancer progression. This systematic review aims to integrate data on IL17's role in various tumors to ...
