College of Medicine: Recent submissions
Now showing items 881-900 of 1731
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What is polypharmacy in people living with HIV/AIDS? A systematic review.
( springer link , 2022 , Article)Polypharmacy in people living with HIV/AIDS (PLWHA) is a rising morbidity that exacts hefty economic burden on health budgets in addition to other adverse clinical outcomes. Despite recent advances, uncertainty remains ... -
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem ... -
Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation ... -
Platelet–Neutrophil Association in NETs-Rich Areas in the Retrieved AIS Patient Thrombi
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Histological structure of thrombi is a strong determinant of the outcome of vascular recanalization therapy, the only treatment option for acute ischemic stroke (AIS) patients. A total of 21 AIS patients from this study ... -
Proteomic profile alterations in porcine conceptuses during early stages of development
( Elsevier , 2021 , Article)The dynamic embryo development during the early stages of gestation requires precise molecular changes, including proteomic ones. We aimed to find unique proteins for porcine conceptuses specifically during the peri-implantation ... -
Nano-targeting vascular remodeling in cancer: Recent developments and future directions
( Elsevier , 2022 , Article Review)Tumor growth and progression are strictly dependent on the adequate blood supply of oxygen and nutrients. The formation of new blood vessels and vascular networks is essential to ensure this demand. Blood vessels also ... -
Social determinants of depression among mid-to-older aged Australians: A prospective study of the effects of neighbourhood disadvantage and crime
( Elsevier , 2022 , Article)BackgroundFew studies examining social determinants of depression have incorporated area level objectively measured crime combined with self-report measures of perceived crime. How these factors may interrelate with ... -
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
( Elsevier , 2023 , Article)Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing ... -
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
( Elsevier , 2021 , Article)Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ... -
Editorial: The effect of COVID-19 on hematological disease diagnosis, management and outcomes
( Frontiers Media S.A. , 2023 , Article)Lee, Chieng, Lau et al. studied the effects of coronavirus disease-2019 (COVID-19) on the clinical presentation, radiological findings, and outcomes of the infection in patients with hemoglobinopathies. They found that the ... -
Metabolic changes after surgical fat removal: Current gaps and suggestions for future studies
( Elsevier , 2023 , Article)Dear Editor, We read with interest the letter by Seretes et al. discussing the findings and limitations of our evidence synthesis regarding the metabolic implications of surgical subcutaneous fat removal (SSFR).1 It is ... -
Angry scientists, angry analysts and angry novelists
( Springer Nature , 2023 , Article)To the Editor: Professor Bonora has written a critique looking back at his career in diabetes research since the 1970s and we reflect on his critique by also looking back at our careers in clinical endocrinology (Professor ... -
Effect of statins on abdominal aortic aneurysm
( Elsevier , 2022 , Article Review)Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ... -
Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs
( Elsevier , 2017 , Article)PurposeThere are no published instruments, which measure tutor motivation for conducting small group tutorials in problem-based learning programs. Therefore, we aimed to develop a motivation for tutoring questionnaire in ... -
Medical Education in Egypt: Historical Background, Current Status, and Challenges
( Elsevier , 2018 , Article)BackgroundFrom its beginnings in 1827, an important goal of medical education in Egypt has been to qualify physicians who can provide high-quality health care services for their local community and other communities in the ... -
The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model
( Elsevier , 2022 , Article)Traumatic Brain Injury (TBI) is one of the leading causes of death and disability worldwide. Aspirin (ASA) and clopidogrel (CLOP) are antiplatelet agents that inhibit platelet aggregation. They are implicated in worsening ... -
Children's longitudinal bodyweight in Australia: Influence of migrant mothers' long-term residency, attachment to, and level of childhood overweight in country-of-birth
( Elsevier , 2022 , Article)Immigration creates opportunities and imposes constraints associated with acculturation. We used the Australian national longitudinal survey of children aged 2 to 17 to evaluate the influence of mothers' long-term residency ... -
Enteric pathogens modulate metabolic homeostasis in the Drosophila melanogaster host
( Elsevier , 2022 , Article)On quotidian basis, living beings work out an armistice with their microbial flora and a scuffle with invading pathogens to maintain a normal state of health. Although producing virulence factors and escaping the host's ... -
An integrative comparative study between ultrasound-guided regional anesthesia versus parenteral opioids alone for analgesia in emergency department patients with hip fractures: A systematic review and meta-analysis
( Elsevier , 2022 , Article Review)BackgroundEmergency physicians play a major role in managing patients with hip fractures. The most commonly used pain management option is parenteral opioids. However, parenteral opioids are subjected to several adverse ... -
Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region
( Elsevier , 2022 , Article)Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide, particularly among children under five years in underdeveloped countries. Most acute gastroenteritis (AGE) cases are attributed to viral ...
