College of Medicine: Recent submissions
Now showing items 1001-1020 of 1518
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An Update on the Molecular and Clinical Characteristics of Apocrine Carcinoma of the Breast
( Elsevier , 2021 , Article)Apocrine carcinoma of the breast is a rare malignancy. According to 2019 WHO classification, apocrine cellular features and a characteristic steroid receptor profile (Estrogen receptor (ER)-negative and androgen receptor ... -
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
( Elsevier , 2022 , Article)Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ... -
In sickness and in health: The politics of public health and their implications during the COVID-19 pandemic
( Wiley , 2021 , Article)Politics is a major player in health, sickness, and death affairs. This article reviews the role of politics in public health and its impact on health outcomes, mortality ratios, and death scenarios amongst the most ... -
IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group’s Criteria
( Elsevier , 2021 , Article)AimsThe approaches used to screen and diagnose gestational diabetes mellitus (GDM) vary widely. We generated a comparable estimate of the global and regional prevalence of GDM by International Association of Diabetes in ... -
IDF Diabetes Atlas: The prevalence of pre-existing diabetes in pregnancy – A systematic reviewand meta-analysis of studies published during 2010–2020
( Elsevier , 2021 , Article)ObjectivesTo estimate the prevalence of pre-existing diabetes in pregnancy from studies published during 2010–2020. MethodsWe searched PubMed, CINAHL, Scopus and other sources for relevant data sources. The prevalence of ... -
Teaching Musculoskeletal Module using dissection videos: feedback from medical students.
( BMC , 2021 , Article)Over the last two decades many medical schools have been exploring alternatives to hands-on cadaver dissection in teaching anatomy. This study aimed at reporting medical students' feedback on using dissection videos in ... -
Value of additional sections: Tissue handling of small biopsies in detecting squamous dysplasia of the uterine cervix
( Elsevier , 2022 , Article)Cervical cancer screening is currently based on high-risk human papillomavirus (HR-HPV) molecular testing, Pap cytology testing, and histologic evaluation of cervical biopsies. As primary HPV screening for cervical cancer ... -
The diagnostic accuracy of HbA , compared to the oral glucose tolerance test, for screening for type 2 diabetes mellitus in Africa-a systematic review and meta-analysis.
( Wiley , 2021 , Other)To assess the diagnostic accuracy of HbA , compared to fasting plasma glucose (FPG) and the oral glucose tolerance test (OGTT), in screening for type 2 diabetes (T2D) in Africa. We systematically searched databases for ... -
Visfatin : An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases
( Wiley , 2021 , Article)Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been implicated in vascular remodeling, vascular ... -
In silico virtual screening of lead compounds for major antigenic sites in respiratory syncytial virus fusion protein.
( Springer , 2021 , Article)Human respiratory syncytial virus (RSV) is a leading ubiquitous respiratory pathogen in newborn infants, young children, and the elderly, with no vaccine available to date. The viral fusion glycoprotein (RSV F) plays an ... -
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
( Frontiers Media , 2021 , Article)Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ... -
Nutm1-rearranged neoplasms: A heterogeneous group of primitive tumors with expanding spectrum of histology and molecular alterations: An updated review
( MDPI , 2021 , Article)Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long arm of chromosome 15) with highly restricted physiologic expression in post-meiotic spermatids, is the oncogenic driver of a group ... -
Fascin in Gynecological Cancers: An Update of the Literature
( MDPI , 2021 , Article)Fascin is an actin-binding protein that is encoded by the gene (located on chromosome 7). It triggers membrane projections and stimulates cell motility in cancer cells. Fascin overexpression has been described in different ... -
HPV and Recurrent Respiratory Papillomatosis: A Brief Review
( MDPI , 2021 , Article)Recurrent Respiratory Papillomatosis (RRP) is a rare but severe manifestation of human papillomavirus (HPV). As our knowledge about HPV infections has expanded, it has become possible to understand the course of RRP disease ... -
DNA Damage/Repair Management in Cancers
( Routledge , 2021 , Book chapter)DNA damage can alter nucleotide sequences and lead to expression of dysfunctional proteins that impact normal cellular physiology. Sources of DNA damage can be endogenous or exogenous and include reactive oxygen species ... -
Infantile hypertrophic pyloric stenosis in Bosnia and Herzegovina: A retrospective cohort study from the largest tertiary care facility
( Elsevier , 2021 , Article)Background Infantile hypertrophic pyloric stenosis (IHPS) is the most common condition requiring surgery in infancy, but the etiology of IHPS is still unclear. The study aimed to analyze the epidemiological and clinical ... -
Interrelation between Sleep Bruxism and Obstructive Sleep Apnea: Literature Review
( Hooghly Sciencedomain International , 2021 , Article Review)Obstructive sleep apnea (OSA) is a clinical risk factor for sleep bruxism (SB). Although no clear causative link has been defined, both conditions are inter related to sleep-related arousal reactions. A literature review ... -
Attitudes and Intentions toward COVID-19 Vaccination among Health Professions Students and Faculty in Qatar
( MDPI , 2021 , Article)A population’s desire to take the COVID-19 vaccine is an important predictor of a country’s future pandemic management. This cross-sectional study examines the impact of psychological and sociodemographic factors on attitudes ... -
The Freeman–Tukey double arcsine transformation for the meta-analysis of proportions: Recent criticisms were seriously misleading
( John Wiley & Sons, Ltd , 2021 , Article)Pooling of proportions in meta-analysis are used to get better and more precise estimates of disease frequency, including cumulative incidence or prevalence. Meta-analysis is of course only useful when there are a limited ... -
Evaluation of Diagnostic Workup and Etiology of Hypercalcemia of Malignancy in a Cohort of 167 551 Patients Over 20 Years.
( Oxford University Press , 2021 , Article)Hypercalcemia of malignancy (HCM) has not been studied in a fashion to determine all possible mechanisms of hypercalcemia in any given patient. The 2 objectives were to assess the completeness of evaluation and to determine ...
