College of Medicine: Recent submissions
Now showing items 361-380 of 1509
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An investigation into the avoidability of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome
( Springer Nature , 2021 , Article)Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rising morbidity amongst hospitalized patients. Whilst clinical protocols for the management of individual DRESS cases have been well established, ... -
Clinical, Radiological, and Outcome Characteristics of Acute Pulmonary Embolism: A 5-year Experience from an Academic Tertiary Center
( HBKU Press , 2022 , Article)Background: Acute pulmonary embolism (PE) is a common and potentially life-threatening condition. This comprehensive study from a Gulf Cooperation Council (GCC) country aimed to evaluate the clinical, radiological, and ... -
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study
( Springer Nature , 2022 , Article)Background and purpose: Uncertainty remains regarding the impact of enteric-coated aspirin (EC-ASA) on secondary prevention of ischemic stroke compared to plain aspirin (P-ASA). Hence, this study was designed to investigate ... -
Commentary: Potentially inappropriate medication among older patients with diabetic kidney disease
( Frontiers Media SA , 2023 , Article)Wang et al. (2020)’s recent report on the burden and morbidity consequences of potentially inappropriate medications (PIMs) in a select cohort of type 2 diabetic mellitus (T2DM) patients was both instructive and an “inflection ... -
The effect of low-dose aspirin on platelet function during pregnancy compared to placebo: An explorative study. A letter to the Editor
( Elsevier , 2022 , Article)We read with interest Bij de Weg et al.’s, recent mechanistic report on the inhibitory effect of Aspirin on platelet function in patients with pre-eclampsia [1]. Compared to placebo, this study found that 80 mg of generic ... -
Seroconversion and safety of Covid-19 vaccines in patients with chronic liver disease and liver transplant: A systematic review
( HBKU Press , 2023 , Article)Background and Aims: As part of the COVID-19 control strategy, a growing number of vaccine portfolios evolved and got fast-tracked through regulatory agencies, with a limited examination of their efficacy and safety in ... -
Association of polypharmacy with incidence of CKD: a retrospective cohort study: a letter to the Editor
( Springer Nature , 2023 , Article)Kimura et al.’s recently published report on a retrospective examination of the Fukushima chronic kidney disease (CKD) patient cohort provides an interesting perspective on this rising therapeutic morbidity [1]. The study ... -
Colchicine and mortality outcomes in patients with coronavirus disease (COVID-19)
( Elsevier , 2023 , Article)One of the therapeutic hallmarks of the ongoing (COVID-19) pandemic has been the different iterations of successful and sometimes unsuccessful attempts at re-purposing of drugs with pre-existing market authorization for ... -
Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses
( Elsevier , 2023 , Article)BackgroundDespite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine ... -
Patch Testing as a Diagnostic Method for DRESS Syndrome That Brings Us Closer to a Certain Result: Letter to the Editor
( Esmon Publicidad S.A. , 2022 , Article)The recent clinical report by García-Paz et al [1] on a case of DRESS syndrome due to amoxicillin makes for interesting reading. In this report, a 26-year-old man presented with a rash whose clinical phenotype (according ... -
What is Polypharmacy in Patients with Chronic Kidney Disease? A Systematic Review
( Elsevier , 2023 , Article)PurposePolypharmacy presents an increasing therapeutic challenge for physicians managing patients with chronic kidney disease (CKD). However, there is a lack of consensus regarding the specific medication count threshold ... -
Maternal depressiveness and infant growth outcomes: Findings from the MAASTHI cohort study in India
( Elsevier , 2023 , Article)ObjectiveThe study aims to examine the association between depressiveness in mothers on infant obesity and stunting at one year of age. MethodsWe enrolled 4829 pregnant women, followed them up at public health facilities ... -
The social media Infodemic of health-related misinformation and technical solutions
( Elsevier , 2024 , Article)This paper discusses the role of social media algorithms in the spread of misinformation during the COVID-19 pandemic. It aims to propose solutions to combat misinformation and promote accurate, evidence-based public health ... -
Metabolic-associated fatty liver disease: a selective review of pathogenesis, diagnostic approaches, and therapeutic strategies.
( Frontiers Media , 2024 , Article Review)Metabolic associated fatty liver disease (MAFLD) is a novel terminology introduced in 2020 to provide a more accurate description of fatty liver disease associated with metabolic dysfunction. It replaces the outdated term ... -
The Effects of Statin Therapy on Circulating Levels of Trimethylamine N-oxide: A Systematic Review and Meta-analysis
( Bentham Science Publishers , 2023 , Article)Background Gut microbiota is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD) through the metabolites, which can induce atherogenesis. One of these metabolites is trimethylamine N-oxide ... -
In patients with Chronic Heart Failure Which Polypharmacy Pheno-groups are associated with adverse health outcomes? (Polypharmacy Pheno-groups and Heart failure outcomes)
( Elsevier , 2023 , Article)BackgroundPatients with heart failure are living longer with the inevitable morbidity of rising medication counts. It remains uncertain what fraction of this ensuing polypharmacy exactly predicts adverse clinical outcomes. ... -
Determination of Medicago orbicularis Antioxidant, Antihemolytic, and Anti-Cancerous Activities and Its Augmentation of Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells
( MDPI , 2023 , Article)The anti-lung cancer properties of the plant Medicago orbicularis have not been explored yet. Therefore, we identified its phytochemical composition and investigated the antioxidant, anti-hemolytic, and anti-cancerous ... -
Facial Nerve Palsy in Hypertriglyceridemia-Induced Pancreatitis: A Case Report and Literature Review.
( Springer , 2023 , Article)Acute pancreatitis is associated with multiple local or systemic complications in response to systemic inflammation that may eventually result in multi-organ failure. Neurological complications are uncommon in acute ... -
Association between pregnancy and severe COVID-19 symptoms in Qatar: A cross-sectional study.
( PLOS Global Public Health , 2023 , Article)There is inconclusive evidence whether pregnancy exacerbates COVID-19 symptoms or not, and scarce data from the Middle East and North Africa region. The aim of this study was to investigate the association between pregnancy ... -
Epidemiology and early bacterial colonization of minor and moderate pediatric burns: A retrospective study from a developing country
( Elsevier , 2023 , Article)ObjectivesInfection is still the leading cause of morbidity and mortality among burn patients worldwide. Isolation and identification of pediatric burn wound bacterial colonizers can prevent infection and improve burn ...