College of Medicine: Recent submissions
Now showing items 701-720 of 1514
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Prevalence and global trends of polypharmacy in patients with chronic liver disease: A systematic review and meta-analysis
( Wolters Kluwer Health , 2023 , Article)Background: Despite its central role in drug metabolism, the exact prevalence estimates and factors affecting global trends of polypharmacy in patients with chronic liver disease (CLD) have remained unexamined. The aim of ... -
Applications of Artificial Intelligence in Thalassemia: A Comprehensive Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Thalassemia is an autosomal recessive genetic disorder that affects the beta or alpha subunits of the hemoglobin structure. Thalassemia is classified as a hypochromic microcytic anemia and a definitive diagnosis of thalassemia ... -
Chronic Wound Healing Models
( American Chemical Society (ACS) , 2023 , Article)In this paper, we review and analyze the commonly available wound healing models reported in the literature and discuss their advantages and issues, considering their relevance and translational potential to humans. Our ... -
Clinical Phenotypes of PCOS: a Cross-Sectional Study
( Springer , 2023 , Article)This cross-sectional study examines the Doi-Alshoumer PCOS clinical phenotype classification in relation to measured clinical and biochemical characteristics of women with polycystic ovary syndrome (PCOS). Two cohorts of ... -
A Bibliometric Analysis and Visualization of Decision Support Systems for Healthcare Referral Strategies
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: The referral process is an important research focus because of the potential consequences of delays, especially for patients with serious medical conditions that need immediate care, such as those with metastatic ... -
Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model
( Elsevier , 2023 , Article)Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ... -
The Association Between Inflammatory Bowel Disease and Exposure to Tobacco Smoking: A Case-Control Study in Qatar
( Dove Medical Press , 2023 , Article)Objective: This research investigated the association between childhood and adulthood tobacco smoking exposure with ulcerative colitis (UC) and Crohn’s disease (CD) in Qatar. Study Design and Setting: In this case-control ... -
The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection
( Frontiers Media , 2023 , Article)Background: The cross-protective nature of Bacillus Calmette-Guerin (BCG) vaccine against SARS-CoV-2 virus was previously suggested, however its effect in COVID-19 patients with type 2 diabetes (T2D) and the underlying ... -
Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
( MDPI , 2023 , Article)Cancer is the second most life-threatening disease and has become a global health and economic problem worldwide. Due to the multifactorial nature of cancer, its pathophysiology is not completely understood so far, which ... -
Association Between Metabolic Syndrome and Decline in Cognitive Function: A Cross-Sectional Study
( Dave Medical Press Limited, , 2023 , Article)Aim: We investigated whether metabolic syndrome (MetS) is associated with a decline in cognitive function in a cohort of middle-aged and elderly individuals without known cognitive dysfunction diseases in Qatar. Methods: ... -
Validation of Doi's weighted average glucose as a measure of post-load glucose excursion for clinical use.
( Biomolecules and Biomedicine , 2023 , Article)In this study, we examined the performance of a novel index of glucose excursion (Doi’s weighted average glucose [dwAG]) in relation to the conventional measure of area under the oral glucose tolerance test (A-GTT) and the ... -
An updated overview of cyanidins for chemoprevention and cancer therapy
( Elsevier , 2023 , Article Review)Anthocyanins are colored polyphenolic compounds that belong to the flavonoids family and are largely present in many vegetables and fruits. They have been used in traditional medicine in many cultures for a long time. The ... -
Sickness absenteeism among primary health care workers in Qatar before and during the COVID-19 pandemic
( BioMed Central Ltd , 2023 , Article)Objectives: To explore the patterns, trends, nature, and extent of changes in sickness absence among health care workers (HCWs) at the Primary Health Care Corporation (PHCC) in Qatar-during the COVID-19 pandemic compared ... -
The Arabic Questionnaire for Psychotic Experiences in patients with psychotic disorders: a clinical validation
( BioMed Central Ltd , 2023 , Article)Background: Psychotic experiences are reported in the general population. The Questionnaire for Psychotic Experiences (QPE) was created to test the phenomenological features of these experiences and compare them with those ... -
Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
( BioMed Central Ltd , 2023 , Article)Background: The mechanism of tumor immune escape and progression in colorectal cancer (CRC) is widely investigated in-vitro to help understand and identify agents that might play a crucial role in response to treatment and ... -
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
( Nature Research , 2023 , Article)Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the ... -
Applications of Machine Learning in Chronic Myeloid Leukemia
( MDPI , 2023 , Article)Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by dysregulated growth and the proliferation of myeloid cells in the bone marrow caused by the BCR-ABL1 fusion gene. Clinically, CML demonstrates ... -
Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
( Taylor and Francis Ltd. , 2023 , Article)Purpose: Low bicarbonate, a hallmark of metabolic acidosis is associated with various diseases. This study investigated associations between bicarbonate levels with prediabetes and subclinical inflammation among healthy ... -
The impact of prior obesity surgery on glucose metabolism after body contouring surgery: A pilot study.
( Europe PMC , 2023 , Article)Body contouring surgery enhances physical appearance by means of surgical subcutaneous fat removal (SSFR). However, it remains unclear how SSFR may affect glucose metabolism and its broader effects on the endocrine system, ... -
ANO4 Expression Is a Potential Prognostic Biomarker in Non-Metastasized Clear Cell Renal Cell Carcinoma
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Background: Over the past decade, transcriptome profiling has elucidated many pivotal pathways involved in oncogenesis. However, a detailed comprehensive map of tumorigenesis remains an enigma to solve. Propelled research ...